SCHEMBL8770332

SCHEMBL8770332

NNC(=O)CCCc1ccc([N+](=O)[O-])cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.53
KMT2A Q03164 3/20 0.51
NPC1 O15118 2/20 0.51
RAB9A P51151 2/20 0.51
MEN1 O00255 2/20 0.51
ALDH1A1 P00352 2/20 0.51
HDAC1 Q13547 2/20 0.50
HDAC3 O15379 1/20 0.50
HDAC2 Q92769 1/20 0.50
HDAC8 Q9BY41 1/20 0.50
MAPT P10636 3/20 0.48
CA12 O43570 1/20 0.47
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
CA4 P22748 1/20 0.47
CA5A P35218 1/20 0.47
CA7 P43166 1/20 0.47
CA9 Q16790 1/20 0.47
CA14 Q9ULX7 1/20 0.47
LOXL2 Q9Y4K0 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2790377 0.90 TSHR (0.56) TSHRKMT2ANPC1RAB9AMEN1
SCHEMBL22570415 0.86 HDAC1 (0.66) TSHRKMT2ANPC1RAB9AMEN1
SCHEMBL2850348 0.83 TSHR (0.59) TSHRKMT2AMEN1ALDH1A1MAPT
SCHEMBL28453370 0.81 HDAC1 (0.68) TSHRALDH1A1HDAC1HDAC3HDAC2
SCHEMBL2494960 0.80 KMT2A (0.59) KMT2AMEN1ALDH1A1MAPTLOXL2
SCHEMBL135651 0.80 TSHR (0.59) TSHRKMT2ANPC1RAB9AMEN1
SCHEMBL7717557 0.80 TSHR (0.51) TSHRKMT2ANPC1RAB9AMEN1
SCHEMBL8934569 0.79 TSHR (0.58) TSHRKMT2AMEN1ALDH1A1MAPT
Hydrochloric Acid SCHEMBL5030930 0.79 TSHR (0.58) TSHRKMT2ANPC1RAB9AMEN1
SCHEMBL5030925 0.79 TSHR (0.58) TSHRKMT2ANPC1RAB9AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0534596-B1 Novel hydrazine compound, process for the preparation of the same, and non-linear optical organic material MITSUI PETROCHEMICAL IND (JP) 1997-09-17 EP disclosed
US-5445888-A Optical wavelength conversion element; electrooptical element MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1995-08-29 US disclosed
EP-0534596-A2 Novel hydrazine compound, process for the preparation of the same, and non-linear optical organic material MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1993-03-31 EP disclosed