Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 14/20 | 0.68 |
| ▸ | HDAC2 | Q92769 | 9/20 | 0.68 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.68 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.68 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.62 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.62 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.62 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.62 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.62 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.62 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.62 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.59 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22570415 | 0.95 | HDAC1 (0.66) | HDAC1HDAC2HDAC8HDAC3HDAC6 | |
| SCHEMBL6821944 | 0.82 | TSHR (0.58) | HDAC1HDAC2HDAC8HDAC3ALDH1A1 | |
| SCHEMBL1527806 | 0.82 | MAPT (0.58) | HDAC1HDAC2HDAC8HDAC3HDAC6 | |
| SCHEMBL8770332 | 0.81 | TSHR (0.53) | HDAC1HDAC2HDAC8HDAC3ALDH1A1 | |
| SCHEMBL18913824 | 0.81 | TSHR (0.69) | ALDH1A1TSHR | |
| SCHEMBL154515 | 0.81 | MAPT (0.61) | HDAC1HDAC2HDAC8HDAC3HDAC6 | |
| SCHEMBL153108 | 0.81 | MAPT (0.61) | HDAC1HDAC2HDAC8HDAC3HDAC6 | |
| SCHEMBL2944805 | 0.81 | MAPT (0.61) | HDAC1HDAC2HDAC8HDAC3HDAC6 | |
| SCHEMBL7723398 | 0.81 | TSHR (0.56) | HDAC1HDAC2HDAC8HDAC3ALDH1A1 | |
| SCHEMBL2945405 | 0.81 | MAPT (0.61) | HDAC1HDAC2HDAC8HDAC3HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111566116-A | Novel metal complex, method for producing same, and method for producing gamma-lactam compound using same | 基础科学研究院 | 2020-08-21 | — | — | CN | disclosed |