Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 5/20 | 0.56 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.56 |
| ▸ | S1PR2 | O95136 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.47 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
| ▸ | RXRG | P48443 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8770430 | 0.86 | S1PR1 (0.52) | S1PR1S1PR3S1PR2ALDH1A1HSD17B10 | |
| SCHEMBL21879789 | 0.84 | CPA3 (0.55) | S1PR1S1PR3S1PR2 | |
| SCHEMBL27650570 | 0.84 | FFAR4 (0.54) | ALDH1A1HSD17B10MAPTRXFP1FFAR4 | |
| SCHEMBL27650627 | 0.84 | FFAR4 (0.54) | ALDH1A1HSD17B10MAPTRXFP1FFAR4 | |
| SCHEMBL25173315 | 0.82 | MAPT (0.69) | S1PR1S1PR3S1PR2ALDH1A1HSD17B10 | |
| SCHEMBL8079984 | 0.82 | MAPT (0.69) | S1PR1S1PR3S1PR2ALDH1A1HSD17B10 | |
| Dimethylamine SCHEMBL20994614 | 0.81 | HDAC3 (0.52) | — | |
| SCHEMBL27921120 | 0.80 | PLA2G4B (0.49) | S1PR1S1PR3ALDH1A1CYSLTR2CYSLTR1 | |
| SCHEMBL20853926 | 0.80 | ALDH1A1 (0.69) | S1PR1S1PR3S1PR2ALDH1A1HSD17B10 | |
| SCHEMBL25167617 | 0.78 | S1PR1 (0.71) | S1PR1S1PR3S1PR2ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0794799-A2 | USE OF METAL COMPLEXES AS LIVER AND GALL BLADDER RADIODIAGNOSIS AGENTS IN COMPUTER TOMOGRAPHY | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-09-17 | — | — | EP | disclosed |
| WO-1996016677-A2 | USE OF METAL COMPLEXES AS LIVER AND GALL BLADDER RADIODIAGNOSIS AGENTS IN COMPUTER TOMOGRAPHY | SCHERING AKTIENGESELLSCHAFT (DE) | 1996-06-06 | — | — | WO | disclosed |