SCHEMBL8770439

SCHEMBL8770439

Nc1cc2c(cc1Br)C(=O)c1ccccc1C2=O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.55
NPC1 O15118 5/20 0.55
RAB9A P51151 5/20 0.55
SMN1; SMN2 Q16637 4/20 0.55
MAPK1 P28482 3/20 0.55
TP53 P04637 1/20 0.55
CYP3A4 P08684 1/20 0.55
TSHR P16473 1/20 0.55
TDP1 Q9NUW8 1/20 0.55
MEN1 O00255 4/20 0.53
POLB P06746 4/20 0.53
KMT2A Q03164 4/20 0.53
MAPT P10636 4/20 0.53
HTT P42858 3/20 0.53
L3MBTL1 Q9Y468 2/20 0.53
NSD2 O96028 2/20 0.50
CDC25B P30305 1/20 0.50
PTPRC P08575 5/20 0.48
LMNA P02545 3/20 0.48
ADORA2A P29274 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30804365 1.00 ALDH1A1 (0.55) ALDH1A1NPC1RAB9ASMN1; SMN2MAPK1
SCHEMBL1143212 0.96 ALDH1A1 (0.52) ALDH1A1NPC1RAB9ASMN1; SMN2MAPK1
SCHEMBL9354025 0.87 CA1 (0.40) ALDH1A1NPC1RAB9ASMN1; SMN2MAPK1
SCHEMBL6029304 0.84 NPC1 (0.67) ALDH1A1NPC1RAB9ASMN1; SMN2MAPK1
SCHEMBL571761 0.84 MEN1 (0.63) ALDH1A1NPC1RAB9ASMN1; SMN2MAPK1
SCHEMBL24730390 0.80 PTPRC (0.59) ALDH1A1NPC1RAB9ASMN1; SMN2MAPK1
SCHEMBL6230652 0.80 NPC1 (0.61) ALDH1A1NPC1RAB9ASMN1; SMN2MAPK1
SCHEMBL8770711 0.79 ALDH1A1 (0.55) ALDH1A1NPC1RAB9ASMN1; SMN2MAPK1
SCHEMBL14629464 0.76 SMN1; SMN2 (0.52) ALDH1A1NPC1RAB9ASMN1; SMN2MAPK1
SCHEMBL10047411 0.75 MEN1 (0.50) ALDH1A1NPC1RAB9ASMN1; SMN2MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4288362-A Monoazo pigments containing a quinazo linonylacetoacetanilide coupling component BAYER AKTIENGESELLSCHAFT (DE) 1981-09-08 US claimed
US-4139543-A Manufacture of 2-amino-3-bromoanthraquinone BASF AKTIENGESELLSCHAFT (DE) 1979-02-13 US claimed
CN-117700767-A Preparation method of secondary amine resin, polyurethane and MBBR filler 厦门理工学院 2024-03-15 CN disclosed
EP-0585873-B1 Method of preparing disazo pigments CLARIANT GMBH (DE) 1997-12-29 EP disclosed
EP-0653416-B1 Process for the preparation of benzoyl amino anthraquinone compounds BASF AG (DE) 1997-09-24 EP disclosed
US-5559216-A AZO COUPLING HOECHST AG (DE) 1996-09-24 US disclosed
US-5525743-A Preparation of anthraquinone imide compounds BASF AKTIENGESELLSCHAFT (DE) 1996-06-11 US disclosed
EP-0649833-B1 Process for the preparation of anthraquinonamine compounds BASF AG (DE) 1996-02-28 EP disclosed
US-5493011-A PIGMENTING HIGH MOLECULAR WEIGHT NATURAL OR SYNTHETIC ORGANIC MATERIALS HOECHST AG (DE) 1996-02-20 US disclosed
EP-0653416-A1 Process for the preparation of benzoyl amino anthraquinone compounds BASF Aktiengesellschaft (DE) 1995-05-17 EP disclosed
EP-0649833-A1 Process for the preparation of anthraquinonamine compounds BASF Aktiengesellschaft (DE) 1995-04-26 EP disclosed
US-4157893-A MONO OR DISAZO DYE CONTAINING AN AMINO-SUBSTITUTED PYRIMIDINE RING BASF AKTIENGESELLSCHAFT (DE) 1979-06-12 US disclosed
US-4154577-A Uniformly disperse dyed water-swellable cellulosic fibers BASF AKTIENGESELLSCHAFT (DE) 1979-05-15 US disclosed
US-4150943-A Uniformly dyed water-swellable cellulosic fibers BASF AKTIENGESELLSCHAFT (DE) 1979-04-24 US disclosed
US-4146535-A Azo dyes having a 3-cyano- or 3-carbamoyl-2,6-diamino-pyridine coupling component BASF AKTIENGESELLSCHAFT (DE) 1979-03-27 US disclosed
US-4139543-A Manufacture of 2-amino-3-bromoanthraquinone BASF AKTIENGESELLSCHAFT (DE) 1979-02-13 US disclosed
US-4139543-A Manufacture of 2-amino-3-bromoanthraquinone BASF AKTIENGESELLSCHAFT (DE) 1979-02-13 US disclosed
US-4139543-A Manufacture of 2-amino-3-bromoanthraquinone BASF AKTIENGESELLSCHAFT (DE) 1979-02-13 US disclosed
US-4083684-A AZO DYES, WASHFASTNESS, PHOTOSTABILITY, SOLVENT RESISTANCE BASF AKTIENGESELLSCHAFT (DT) 1978-04-11 US disclosed
US-4052371-A AZO PIGMENT OR DYE HAVING A NAPHTHYL-QUINAZALONE COUPLING COMPONENT BASF AKTIENGESELLSCHAFT (DT) 1977-10-04 US disclosed