SCHEMBL8770491

SCHEMBL8770491

OCc1nnc(S)s1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11786548 0.97
SCHEMBL11431837 0.80
SCHEMBL8770450 0.80
SCHEMBL10403239 0.72 F2 (0.39)
SCHEMBL19435 0.69
SCHEMBL11590354 0.69
SCHEMBL11767701 0.69 ALDH1A1 (0.46)
SCHEMBL282156 0.68
SCHEMBL11360019 0.68
SCHEMBL18616970 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4081443-A Penicillin oxides SHIONOGI & CO., LTD. (JA) 1978-03-28 US claimed
EP-0796890-A1 Vulcanizable acrylic rubber composition ENICHEM S.p.A. (IT) 1997-09-24 EP disclosed
US-4374994-A Process for preparation of 5-mercaptotetrazolyl-1-acetic acid BRISTOL-MYERS COMPANY (US) 1983-02-22 US disclosed
US-4271295-A HALOGENATION STEP SHIONOGI & CO., LTD. (JP) 1981-06-02 US disclosed
US-4271296-A CEPHALOSPORINS AND DERIVATIVES SHIONOGI & CO., LTD. (JP) 1981-06-02 US disclosed
US-4233216-A INTERMEDIATES FOR OXADETHIACEPHALOSPORINS SHIONOGI & CO., LTD. (JP) 1980-11-11 US disclosed
US-4220766-A FROM PENICILLINS SHIONOGI & CO., LTD. (JP) 1980-09-02 US disclosed
US-4205166-A 7-Substituted-3-aminoalkyl-, acylaminoalkyl-, or hydroxyalkyl-substituted heterocyclic thiomethyl-3-cephem-4-carboxylic acid derivatives and preparation thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1980-05-27 US disclosed
US-4153693-A 1,4-Dihydro-4-oxo-pyridylacetamido cephalosporins and their utilization as medicinal agents for combating bacterial infections MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1979-05-08 US disclosed
US-4128510-A 2,5-DIMERCAPTO-1,3,4-THIADIAZOLES HERCULES INCORPORATED (US) 1978-12-05 US disclosed
US-4081443-A Penicillin oxides SHIONOGI & CO., LTD. (JA) 1978-03-28 US disclosed
US-4077965-A Aminoalkyl- or hydroxyalkyl-substituted thiadiazole derivatives FUJISAWA PHARMACEUTICAL CO., LTD. (JA) 1978-03-07 US disclosed
US-4058521-A 2-Halomethyl-2-nucleophilic substituted methyl penicillins SHIONOGI & CO., LTD. (JA) 1977-11-15 US disclosed
US-3946000-A BACTERICIDES, POULTRY, ANIMALS BRISTOL-MYERS COMPANY (US) 1976-03-23 US disclosed