P-Xylene

P-Xylene

SCHEMBL8770845

CC(=O)OCCO.Cc1ccc(C)cc1

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.48
ALDH1A1 P00352 6/20 0.42
HSD17B10 Q99714 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.41
CHRM5 P08912 2/20 0.40
CHRM1 P11229 2/20 0.40
CHRM3 P20309 2/20 0.40
PGR P06401 1/20 0.40
CHRM2 P08172 1/20 0.40
CHRM4 P08173 1/20 0.40
HTR1A P08908 1/20 0.40
CHRNB2 P17787 1/20 0.40
TBXA2R P21731 1/20 0.40
CHRNB4 P30926 1/20 0.40
CHRNA3 P32297 1/20 0.40
CHRNA7 P36544 1/20 0.40
CHRNA4 P43681 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
CHRNA10 Q9GZZ6 1/20 0.40
CHRNA9 Q9UGM1 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
P-Xylene SCHEMBL10949353 0.92 ALDH1A1 (0.48) LMNAALDH1A1L3MBTL1SMN1; SMN2TSHR
Toluene SCHEMBL11129618 0.90 ALDH1A1 (0.50) LMNAALDH1A1SMN1; SMN2TSHRCES2
P-Xylene SCHEMBL11399447 0.89 LMNA (0.54) LMNAALDH1A1HSD17B10L3MBTL1CHRM5
SCHEMBL3070371 0.83 ALDH1A1 (0.55) LMNAALDH1A1HSD17B10CHRM5CHRM1
SCHEMBL27796 0.83
P-Xylene SCHEMBL7256576 0.83 ALDH1A1 (0.52) LMNAALDH1A1HSD17B10L3MBTL1CHRM5
Acetic Acid Butyl Ester SCHEMBL7898896 0.81 ALDH1A1 (0.56) LMNAALDH1A1L3MBTL1SMN1; SMN2TSHR
SCHEMBL25232908 0.81
Water SCHEMBL58538 0.81
SCHEMBL21580547 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10071711-B2 Coating agent for wiper blade rubber and wiper blade rubber using same FUKOKU CO., LTD. (JP) 2018-09-11 US disclosed
EP-3075802-A1 COATING AGENT FOR WIPER BLADE RUBBER, AND WIPER BLADE RUBBER USING SAME Fukoku Co., Ltd. (JP) 2016-10-05 EP disclosed
US-20160272158-A1 COATING AGENT FOR WIPER BLADE RUBBER AND WIPER BLADE RUBBER USING SAME FUKOKU CO., LTD. (JP) 2016-09-22 US disclosed
EP-0368320-B1 Heat transfer image-receiving sheet DAINIPPON PRINTING CO LTD (JP) 1997-10-08 EP disclosed
US-5023114-A Method of hydrophilic coating of plastics BIOCOAT INCORPORATED 1991-06-11 US disclosed
US-4990485-A Dye receiving layer of graft polymer with releasing segments of polysiloxanes, fluorinated carbons and long chain alkyls DAI NIPPON INSATSU KABUSHIKI KAISHA (JP) 1991-02-05 US disclosed
EP-0368320-A2 Heat transfer image-receiving sheet DAI NIPPON INSATSU KABUSHIKI KAISHA (JP) 1990-05-16 EP disclosed
US-4801475-A Method of hydrophilic coating of plastics BIOCOAT INCORPORATED 1989-01-31 US disclosed
US-4240585-A Electrostatic spraying apparatus with repelling electrode means and gas shroud PPG INDUSTRIES, INC. (US) 1980-12-23 US disclosed
US-3960824-A Mercaptan initiated polymerization process carried out in the presence of oxygen CELANESE COATINGS & SPECIALTIES COMPANY (US) 1976-06-01 US disclosed