Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 6/20 | 0.71 |
| ▸ | CA9 | Q16790 | 6/20 | 0.71 |
| ▸ | CA2 | P00918 | 5/20 | 0.71 |
| ▸ | CA1 | P00915 | 2/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.71 |
| ▸ | USP2 | O75604 | 1/20 | 0.71 |
| ▸ | LMNA | P02545 | 1/20 | 0.71 |
| ▸ | BCHE | P06276 | 1/20 | 0.71 |
| ▸ | CA4 | P22748 | 1/20 | 0.71 |
| ▸ | CA6 | P23280 | 1/20 | 0.71 |
| ▸ | CA5A | P35218 | 1/20 | 0.71 |
| ▸ | CA7 | P43166 | 1/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.71 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.71 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | ALPI | P09923 | 5/20 | 0.44 |
| ▸ | ALPL | P05186 | 4/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Saccharin SCHEMBL28389154 | 1.00 | CA12 (0.71) | CA12CA9CA2CA1KDM4E | |
| Saccharin SCHEMBL8024547 | 0.86 | CA12 (0.81) | CA12CA9CA2CA1KDM4E | |
| Saccharin SCHEMBL7156459 | 0.85 | CA12 (0.73) | CA12CA9CA2CA1KDM4E | |
| Saccharin SCHEMBL27898163 | 0.85 | CA12 (0.79) | CA12CA9CA2CA1KDM4E | |
| Saccharin SCHEMBL8061288 | 0.85 | CA12 (0.79) | CA12CA9CA2CA1KDM4E | |
| Saccharin SCHEMBL29037506 | 0.84 | CA12 (0.92) | CA12CA9CA2CA1KDM4E | |
| Saccharin SCHEMBL28045129 | 0.84 | CA12 (0.92) | CA12CA9CA2CA1KDM4E | |
| Saccharin SCHEMBL8935949 | 0.84 | CA12 (0.92) | CA12CA9CA2CA1KDM4E | |
| Saccharin SCHEMBL28120403 | 0.84 | CA12 (0.92) | CA12CA9CA2CA1KDM4E | |
| Saccharin SCHEMBL3816 | 0.84 | CA12 (1.00) | CA12CA9CA2CA1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0795323-A1 | Stable gelified composition containing oxygen- and/or water-sensitive lipophilic actives | L'OREAL (FR) | 1997-09-17 | — | — | EP | disclosed |