Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29234371 | 0.89 | PPARG (0.47) | AGTR1LMNACYP1A2RAB9ACA1 | |
| SCHEMBL29234372 | 0.89 | PPARG (0.47) | AGTR1LMNACYP1A2RAB9ACA1 | |
| SCHEMBL30669716 | 0.85 | PPARG (0.49) | AGTR1LMNACYP1A2RAB9ACA1 | |
| SCHEMBL6055320 | 0.85 | PPARG (0.49) | AGTR1LMNACYP1A2RAB9ACA1 | |
| SCHEMBL28986023 | 0.85 | ADRA2A (0.50) | AGTR1LMNACYP1A2RAB9ACA1 | |
| SCHEMBL14692188 | 0.84 | ADRA2A (0.40) | AGTR1LMNACYP1A2POLBHTT | |
| SCHEMBL30988788 | 0.84 | CYP1A2 (0.55) | AGTR1LMNACYP1A2RAB9ACA1 | |
| SCHEMBL21816513 | 0.84 | CYP1A2 (0.55) | AGTR1LMNACYP1A2RAB9ACA1 | |
| SCHEMBL6481118 | 0.84 | CYP1A2 (0.55) | AGTR1LMNACYP1A2RAB9ACA1 | |
| SCHEMBL11145074 | 0.83 | RAB9A (0.44) | AGTR1LMNACYP1A2RAB9ACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0451668-B1 | Process for the production of optically active alkyl 3-aryl-3-hydroxypropionates | CHISSO CORP (JP) | 1997-08-13 | — | — | EP | disclosed |
| US-5202457-A | Enzyme catalyzed transesterification, resolution of optical active alkyl 3-aryl-3-hydroxypropionate | CHISSO CORPORATION (JP) | 1993-04-13 | — | — | US | disclosed |
| EP-0451668-A2 | Optically active alkyl 3-aryl-3-hydroxypropionates and a method for producing thereof | CHISSO CORPORATION (JP) | 1991-10-16 | — | — | EP | disclosed |