Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPMT | P51580 | 1/20 | 0.41 |
| ▸ | GRN | P28799 | 6/20 | 0.39 |
| ▸ | SORT1 | Q99523 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 2/20 | 0.34 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.33 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6779507 | 0.79 | TPMT (0.38) | TPMTGRNSORT1MEN1KMT2A | |
| SCHEMBL28610276 | 0.76 | AKR1C3 (0.46) | TPMTGRNSORT1MEN1KMT2A | |
| SCHEMBL687445 | 0.76 | LMNA (0.52) | MEN1KMT2AMAPTLMNAKDM4E | |
| SCHEMBL295743 | 0.76 | LMNA (0.52) | MEN1KMT2AMAPTLMNAKDM4E | |
| SCHEMBL7056950 | 0.76 | LMNA (0.52) | MEN1KMT2AMAPTLMNAKDM4E | |
| SCHEMBL5163504 | 0.72 | AKR1C3 (0.45) | MEN1KMT2AMAPTLMNAAKR1C3 | |
| SCHEMBL20868405 | 0.72 | LMNA (0.50) | GRNSORT1MEN1KMT2AMAPT | |
| SCHEMBL20868524 | 0.72 | LMNA (0.50) | GRNSORT1MEN1KMT2AMAPT | |
| SCHEMBL5929629 | 0.71 | LMNA (0.42) | MEN1KMT2AMAPTLMNAAKR1C3 | |
| SCHEMBL5162907 | 0.71 | LMNA (0.42) | MEN1KMT2AMAPTLMNAAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0451668-B1 | Process for the production of optically active alkyl 3-aryl-3-hydroxypropionates | CHISSO CORP (JP) | 1997-08-13 | — | — | EP | disclosed |