Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.73 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.56 |
| ▸ | CTSA | P10619 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.53 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.50 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3443228 | 0.89 | SMN1; SMN2 (0.66) | SMN1; SMN2KMT2ANR4A2MAOBALOX5 | |
| SCHEMBL8770884 | 0.87 | KMT2A (0.60) | SMN1; SMN2KMT2ANR4A2MAOBALOX5 | |
| SCHEMBL8770913 | 0.84 | KMT2A (0.57) | SMN1; SMN2KMT2ANR4A2MAOBALOX5 | |
| SCHEMBL10317574 | 0.84 | FFAR1 (0.63) | SMN1; SMN2KMT2ANR4A2MAOBALOX5 | |
| SCHEMBL8771189 | 0.84 | FFAR1 (0.63) | SMN1; SMN2KMT2ANR4A2MAOBALOX5 | |
| SCHEMBL8181061 | 0.84 | KMT2A (0.58) | SMN1; SMN2KMT2ANR4A2MAOBALOX5 | |
| SCHEMBL3443080 | 0.84 | KMT2A (0.58) | SMN1; SMN2KMT2ANR4A2MAOBALOX5 | |
| SCHEMBL9188249 | 0.84 | KMT2A (0.58) | SMN1; SMN2KMT2ANR4A2MAOBALOX5 | |
| SCHEMBL8770948 | 0.83 | KMT2A (0.56) | SMN1; SMN2KMT2ANR4A2MAOBALOX5 | |
| SCHEMBL13315407 | 0.82 | KMT2A (0.55) | SMN1; SMN2KMT2ANR4A2MAOBALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0451668-B1 | Process for the production of optically active alkyl 3-aryl-3-hydroxypropionates | CHISSO CORP (JP) | 1997-08-13 | — | — | EP | disclosed |
| US-5202457-A | Enzyme catalyzed transesterification, resolution of optical active alkyl 3-aryl-3-hydroxypropionate | CHISSO CORPORATION (JP) | 1993-04-13 | — | — | US | disclosed |
| EP-0451668-A2 | Optically active alkyl 3-aryl-3-hydroxypropionates and a method for producing thereof | CHISSO CORPORATION (JP) | 1991-10-16 | — | — | EP | disclosed |