Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 5/20 | 0.63 |
| ▸ | MMP12 | P39900 | 1/20 | 0.59 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.57 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.57 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.57 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.56 |
| ▸ | LTA4H | P09960 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10317574 | 1.00 | FFAR1 (0.63) | FFAR1MMP12NR4A1NR4A2NR4A3 | |
| SCHEMBL8182251 | 0.86 | FFAR1 (0.66) | FFAR1MMP12NR4A1NR4A2NR4A3 | |
| SCHEMBL3983305 | 0.86 | FFAR1 (0.64) | FFAR1MMP12NR4A1NR4A2NR4A3 | |
| SCHEMBL1508259 | 0.85 | MAOB (0.57) | FFAR1NR4A1NR4A2NR4A3LTA4H | |
| SCHEMBL8770978 | 0.85 | MAOB (0.57) | FFAR1NR4A1NR4A2NR4A3LTA4H | |
| SCHEMBL22668068 | 0.85 | FFAR1 (0.48) | FFAR1MMP12NR4A1NR4A2NR4A3 | |
| SCHEMBL8771185 | 0.84 | SMN1; SMN2 (0.73) | FFAR1NR4A2KMT2ASMN1; SMN2LMNA | |
| SCHEMBL232540 | 0.83 | LMNA (0.59) | FFAR1NR4A1NR4A2NR4A3LMNA | |
| SCHEMBL8162876 | 0.83 | FFAR1 (0.67) | FFAR1NR4A1NR4A2NR4A3FFAR4 | |
| SCHEMBL5720973 | 0.83 | KMT2A (0.72) | FFAR1MMP12NR4A1NR4A2NR4A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2590930-B1 | SPIROCYCLICALLY SUBSTITUTED 1,3-PROPANE DIOXIDE DERIVATIVES, METHODS FOR THE PRODUCTION THEREOF AND USE OF THE SAME AS MEDICAMENT | SANOFI SA (FR) | 2015-02-25 | — | — | EP | disclosed |
| EP-0451668-B1 | Process for the production of optically active alkyl 3-aryl-3-hydroxypropionates | CHISSO CORP (JP) | 1997-08-13 | — | — | EP | disclosed |
| US-5202457-A | Enzyme catalyzed transesterification, resolution of optical active alkyl 3-aryl-3-hydroxypropionate | CHISSO CORPORATION (JP) | 1993-04-13 | — | — | US | disclosed |
| EP-0451668-A2 | Optically active alkyl 3-aryl-3-hydroxypropionates and a method for producing thereof | CHISSO CORPORATION (JP) | 1991-10-16 | — | — | EP | disclosed |