Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.45 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.45 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.45 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.45 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8770928 | 0.86 | FFAR1 (0.51) | KMT2AALOX5MAOBNR4A2MEN1 | |
| SCHEMBL8770884 | 0.86 | KMT2A (0.60) | KMT2ASMN1; SMN2ALOX5MAOBNR4A2 | |
| SCHEMBL8770913 | 0.84 | KMT2A (0.57) | KMT2ASMN1; SMN2ALOX5MAOBNR4A2 | |
| SCHEMBL8771185 | 0.83 | SMN1; SMN2 (0.73) | KMT2ASMN1; SMN2ALOX5MAOBNR4A2 | |
| SCHEMBL23684597 | 0.83 | SYK (0.51) | KMT2ASMN1; SMN2ALOX5MAOBNR4A2 | |
| SCHEMBL8770863 | 0.82 | L3MBTL1 (0.66) | L3MBTL1 | |
| SCHEMBL3443228 | 0.81 | SMN1; SMN2 (0.66) | KMT2ASMN1; SMN2ALOX5MAOBNR4A2 | |
| SCHEMBL16031455 | 0.81 | KMT2A (0.48) | KMT2ASMN1; SMN2ALOX5MAOBNR4A2 | |
| SCHEMBL16031452 | 0.81 | KMT2A (0.48) | KMT2ASMN1; SMN2ALOX5MAOBNR4A2 | |
| SCHEMBL28857505 | 0.80 | RIPK1 (0.51) | SMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0451668-B1 | Process for the production of optically active alkyl 3-aryl-3-hydroxypropionates | CHISSO CORP (JP) | 1997-08-13 | — | — | EP | disclosed |
| US-5202457-A | Enzyme catalyzed transesterification, resolution of optical active alkyl 3-aryl-3-hydroxypropionate | CHISSO CORPORATION (JP) | 1993-04-13 | — | — | US | disclosed |
| EP-0451668-A2 | Optically active alkyl 3-aryl-3-hydroxypropionates and a method for producing thereof | CHISSO CORPORATION (JP) | 1991-10-16 | — | — | EP | disclosed |