Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 7/20 | 0.46 |
| ▸ | RAB9A | P51151 | 7/20 | 0.44 |
| ▸ | NPC1 | O15118 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1663619 | 0.82 | RAB9A (0.52) | MCHR1RAB9ANPC1MAPTKMT2A | |
| SCHEMBL8769706 | 0.82 | RAB9A (0.58) | MCHR1RAB9ANPC1MAPTKMT2A | |
| SCHEMBL21254703 | 0.81 | MAPT (0.45) | MCHR1RAB9ANPC1MAPTKMT2A | |
| SCHEMBL21254928 | 0.79 | RAB9A (0.55) | MCHR1RAB9ANPC1MAPTKMT2A | |
| SCHEMBL21254471 | 0.78 | MAPT (0.38) | MCHR1RAB9ANPC1MAPTKMT2A | |
| SCHEMBL21254465 | 0.78 | RAB9A (0.40) | MCHR1RAB9ANPC1MAPTKMT2A | |
| SCHEMBL21254499 | 0.77 | RAB9A (0.50) | MCHR1RAB9ANPC1MAPTKMT2A | |
| SCHEMBL21254462 | 0.77 | MAPT (0.45) | MCHR1RAB9ANPC1MAPTKMT2A | |
| SCHEMBL18745976 | 0.77 | KMT2A (0.55) | MCHR1RAB9ANPC1MAPTKMT2A | |
| SCHEMBL1664311 | 0.77 | KMT2A (0.55) | MCHR1RAB9ANPC1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012068406-A2 | USE OF HEMATOPOIETIC GROWTH FACTOR MIMETICS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2012-05-24 | — | — | WO | disclosed |