SCHEMBL8771392

SCHEMBL8771392

CCCc1ccc(C(C)c2ccc(N)cc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GFER P55789 1/20 0.50
MAOB P27338 4/20 0.43
MAOA P21397 2/20 0.43
CA2 P00918 1/20 0.41
ACACB O00763 1/20 0.40
LPL P06858 1/20 0.39
LIPG Q9Y5X9 1/20 0.39
ALDH1A1 P00352 1/20 0.39
CYP3A4 P08684 1/20 0.39
TSHR P16473 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
CYP19A1 P11511 2/20 0.39
MAPT P10636 1/20 0.39
TAAR1 Q96RJ0 1/20 0.39
HTR2A P28223 1/20 0.38
IDO1 P14902 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8099782 0.90 GFER (0.64) GFERMAOBMAOAALDH1A1CYP3A4
SCHEMBL9621041 0.89 LPL (0.46) CA2ACACBLPLLIPGALDH1A1
SCHEMBL27497386 0.89 HTR2A (0.48) GFERMAOBMAOACA2ALDH1A1
SCHEMBL27481229 0.87 HTR2A (0.56) GFERMAOBCA2LPLLIPG
SCHEMBL8085926 0.86 GFER (0.52) GFERMAOBMAOAALDH1A1CYP3A4
SCHEMBL8102434 0.86 MAOB (0.57) GFERMAOBMAOAALDH1A1CYP3A4
SCHEMBL22050369 0.86 GFER (0.52) GFERMAOBMAOACA2LPL
SCHEMBL27497706 0.85 HTR2A (0.59) MAOBCA2LPLLIPGALDH1A1
SCHEMBL27496712 0.85 HTR2A (0.59) MAOBCA2LPLLIPGALDH1A1
SCHEMBL5962 0.85 GFER (0.68) GFERMAOBMAOACA2LPL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1173886-A Polyamic acid, polyimide film and liquid crystal aligning film and liquid crystal display element CHISSO CORP (JP) 1998-02-18 CN disclosed
EP-0799270-A1 POLYAMIC ACID, POLYIMIDE FILM AND LIQUID CRYSTAL ALIGNING FILM AND LIQUID CRYSTAL DISPLAY ELEMENT CHISSO CORPORATION (JP) 1997-10-08 EP disclosed
WO-1997014742-A1 POLYAMIC ACID, POLYIMIDE FILM AND LIQUID CRYSTAL ALIGNING FILM AND LIQUID CRYSTAL DISPLAY ELEMENT CHISSO CORPORATION (JP) 1997-04-24 WO disclosed