Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 2/20 | 0.46 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.46 |
| ▸ | ACACB | O00763 | 2/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ACACA | Q13085 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | PLK1 | P53350 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6546083 | 0.91 | HTR2A (0.50) | LPLLIPGACACBCA2SIGMAR1 | |
| SCHEMBL6547850 | 0.91 | CYP1A2 (0.45) | LPLLIPGACACBESR1PDCD1 | |
| SCHEMBL8771392 | 0.89 | GFER (0.50) | LPLLIPGACACBCA2ALDH1A1 | |
| SCHEMBL28365364 | 0.89 | ESR1 (0.64) | ESR1PDCD1ESR2CD274CA2 | |
| SCHEMBL9621454 | 0.86 | CA2 (0.50) | LPLLIPGESR1CA2PLK1 | |
| SCHEMBL597719 | 0.85 | IDO1 (0.50) | LPLLIPGACACBCA2KMT2A | |
| SCHEMBL2491588 | 0.82 | LPL (0.48) | LPLLIPGACACBCA2KMT2A | |
| SCHEMBL7043601 | 0.81 | ADRB2 (0.48) | LPLLIPGACACBCA2KMT2A | |
| SCHEMBL20036657 | 0.81 | LPL (0.43) | LPLLIPGACACBESR1ESR2 | |
| SCHEMBL9774407 | 0.81 | LPL (0.43) | LPLLIPGACACBESR1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0316014-B1 | METHOD FOR PRODUCING ARYLETHYLENES | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1992-04-01 | — | — | EP | disclosed |
| US-4855519-A | Method for producing arylethylene | NIPPON PETROCHEMICALS COMPANY (JP) | 1989-08-08 | — | — | US | disclosed |
| EP-0316014-A2 | Method for producing arylethylenes | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1989-05-17 | — | — | EP | disclosed |