SCHEMBL8771470

SCHEMBL8771470

Cc1[c]ccc(Cc2ccc(N)cc2)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 4/20 0.52
ALDH1A1 P00352 2/20 0.52
TSHR P16473 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
CYP19A1 P11511 2/20 0.39
CYP17A1 P05093 1/20 0.39
CYP11B1 P15538 1/20 0.39
CYP11B2 P19099 1/20 0.39
GFER P55789 1/20 0.37
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA9 Q16790 1/20 0.36
CA14 Q9ULX7 1/20 0.36
RAB9A P51151 2/20 0.36
POLB P06746 2/20 0.36
NPC1 O15118 1/20 0.36
USP2 O75604 1/20 0.36
MAPK10 P53779 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8902334 0.86 ESR1 (0.38) ALDH1A1CA1CA2GAAESR1
SCHEMBL6444606 0.82 ESR1 (0.33) CYP3A4CYP2C19ESR1ESR2KDM4E
SCHEMBL28752772 0.81 CYP3A4 (0.56) CYP3A4ALDH1A1TSHRTDP1CYP19A1
SCHEMBL2093039 0.81 CALM1 (0.48) CYP3A4ALDH1A1KDM4EMAPT
SCHEMBL27588652 0.77 CYP3A4 (0.47) CYP3A4ALDH1A1TSHRTDP1CYP19A1
SCHEMBL28283318 0.74
SCHEMBL8771519 0.73 CYP3A4 (0.70) CYP3A4ALDH1A1TSHRTDP1CYP19A1
SCHEMBL1304762 0.72 CYP3A4 (1.00) CYP3A4ALDH1A1TSHRTDP1CYP19A1
4,4'-Methylenedianiline SCHEMBL28001 0.72 CYP3A4 (1.00) CYP3A4ALDH1A1TSHRTDP1CYP19A1
SCHEMBL3482770 0.72 CYP3A4 (1.00) CYP3A4ALDH1A1TSHRTDP1CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1173886-A Polyamic acid, polyimide film and liquid crystal aligning film and liquid crystal display element CHISSO CORP (JP) 1998-02-18 CN disclosed
EP-0799270-A1 POLYAMIC ACID, POLYIMIDE FILM AND LIQUID CRYSTAL ALIGNING FILM AND LIQUID CRYSTAL DISPLAY ELEMENT CHISSO CORPORATION (JP) 1997-10-08 EP disclosed
WO-1997014742-A1 POLYAMIC ACID, POLYIMIDE FILM AND LIQUID CRYSTAL ALIGNING FILM AND LIQUID CRYSTAL DISPLAY ELEMENT CHISSO CORPORATION (JP) 1997-04-24 WO disclosed