Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 9/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16522671 | 0.92 | KMT2A (0.47) | KMT2AMEN1MAPK1MAPTPOLB | |
| SCHEMBL3580938 | 0.84 | MAPT (0.46) | KMT2AMEN1MAPK1MAPTPOLB | |
| SCHEMBL13728103 | 0.84 | MAPT (0.46) | KMT2AMEN1MAPK1MAPTPOLB | |
| SCHEMBL23147201 | 0.83 | MAPT (0.45) | KMT2AMEN1MAPTPOLBGLA | |
| SCHEMBL17512605 | 0.82 | MAPK1 (0.53) | KMT2AMEN1MAPK1MAPTTDP1 | |
| SCHEMBL20568542 | 0.81 | ALDH1A1 (0.49) | KMT2AMEN1MAPK1MAPTPOLB | |
| SCHEMBL896209 | 0.80 | MEN1 (0.56) | KMT2AMEN1MAPK1MAPTPOLB | |
| SCHEMBL16505140 | 0.80 | ALDH1A1 (0.43) | KMT2AMEN1MAPK1MAPTTDP1 | |
| SCHEMBL16505139 | 0.80 | ALDH1A1 (0.43) | KMT2AMEN1MAPK1MAPTTDP1 | |
| SCHEMBL8656095 | 0.79 | ALDH1A1 (0.47) | KMT2AMEN1MAPK1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0473267-B1 | Acylaminopyridinecarboxamides, process for their preparation and their use as fungicides | ZENECA LTD (GB) | 1997-10-01 | — | — | EP | disclosed |
| US-5334722-A | For plants | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-08-02 | — | — | US | disclosed |