Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | LIPE | Q05469 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8659729 | 0.85 | MEN1 (0.45) | MEN1KMT2AMAPK1CYP3A4CYP1A2 | |
| SCHEMBL30499570 | 0.85 | MEN1 (0.54) | MEN1KMT2AMAPK1CYP3A4CYP1A2 | |
| SCHEMBL9948150 | 0.85 | MEN1 (0.54) | MEN1KMT2AMAPK1CYP3A4CYP1A2 | |
| SCHEMBL5201975 | 0.85 | MEN1 (0.45) | MEN1KMT2AMAPK1CYP3A4CYP1A2 | |
| SCHEMBL896613 | 0.85 | S1PR3 (0.53) | MEN1KMT2AMAPK1CYP3A4CYP1A2 | |
| SCHEMBL13783520 | 0.85 | MEN1 (0.54) | MEN1KMT2AMAPK1CYP3A4CYP1A2 | |
| SCHEMBL5211782 | 0.81 | KMT2A (0.82) | MEN1KMT2AMAPK1CYP3A4CYP1A2 | |
| SCHEMBL29649689 | 0.81 | KMT2A (0.82) | MEN1KMT2AMAPK1CYP3A4CYP1A2 | |
| SCHEMBL8656095 | 0.80 | ALDH1A1 (0.47) | MEN1KMT2AMAPK1CYP3A4CYP1A2 | |
| SCHEMBL29923851 | 0.80 | ALDH1A1 (0.47) | MEN1KMT2AMAPK1CYP3A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12606541-B2 | PPARg modulators and methods of use | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2026-04-21 | — | — | US | disclosed |
| EP-4240736-A1 | PPAR GAMMA MODULATORS AND METHODS OF USE | Eisai R&D Management Co., Ltd. (JP) | 2023-09-13 | — | — | EP | disclosed |
| CN-116635380-A | PPARgamma modulators and methods of use | 卫材R&D管理有限公司 | 2023-08-22 | — | — | CN | disclosed |
| US-20230062861-A1 | PPARg MODULATORS AND METHODS OF USE | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2023-03-02 | — | — | US | disclosed |
| US-20230062861-A1 | PPARg MODULATORS AND METHODS OF USE | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2023-03-02 | — | — | US | disclosed |
| WO-2022099144-A1 | ΡΡΑRγ MODULATORS AND METHODS OF USE | Eisai R&D Mangement Co., Ltd. (JP) | 2022-05-12 | — | — | WO | disclosed |
| WO-2022099144-A1 | ΡΡΑRγ MODULATORS AND METHODS OF USE | Eisai R&D Mangement Co., Ltd. (JP) | 2022-05-12 | — | — | WO | disclosed |
| EP-2254416-B1 | HERBICIDAL COMPOUNDS | SYNGENTA LTD (GB) | 2016-09-07 | — | — | EP | disclosed |
| EP-2254416-B1 | HERBICIDAL COMPOUNDS | SYNGENTA LTD (GB) | 2016-09-07 | — | — | EP | disclosed |
| US-8653078-B2 | Herbicidal pyrido[2,3-b]pyrazines | SYNGENTA LIMITED | 2014-02-18 | — | — | US | disclosed |
| US-20100167931-A1 | HETEROCYCLICALLY SUBSTITUTED HETEROCYCLYLCARBOXYLIC ACID DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2010-07-01 | — | — | US | disclosed |
| CN-101679443-A | Heterocyclically substituted heterocyclyl carboxylic acid derivatives | BAYER CROPSCIENCE AG | 2010-03-24 | — | — | CN | disclosed |
| EP-2158204-A2 | HETEROCYCLICALLY SUBSTITUTED HETEROCYCLYL CARBOXYLIC ACID DERIVATIVES | Bayer CropScience AG (DE) | 2010-03-03 | — | — | EP | disclosed |
| US-20090275589-A1 | Pyridazine Compound and Use Thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-11-05 | — | — | US | disclosed |
| WO-2009090402-A2 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2009-07-23 | — | — | WO | disclosed |
| EP-2014661-A1 | Hererocyclically substituted heterocyclic carboxylic acid derivates | Bayer CropScience AG (DE) | 2009-01-14 | — | — | EP | disclosed |
| WO-2008151735-A2 | HETEROCYCLICALLY SUBSTITUTED HETEROCYCLYL CARBOXYLIC ACID DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2008-12-18 | — | — | WO | disclosed |
| EP-1958946-A1 | PYRIDAZINE COMPOUND AND USE THEREOF | Sumitomo Chemical Company, Limited (JP) | 2008-08-20 | — | — | EP | disclosed |
| WO-2007101859-A1 | SUBSTITUTED PYRAZOLOPYRIMIDINES, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF FOR CONTROLLING PARASITIC FUNGI AND AGENTS CONTAINING THE LATTER | BASF SE (DE) | 2007-09-13 | — | — | WO | disclosed |
| WO-2006122740-A2 | 7-AMINO-6-HETARYLIMIDAZOLO[1,2-A]PYRIMIDINE COMPOUNDS AND USE THEREOF FOR CONTROLLING HARMFUL FUNGI | BASF AKTIENGESELLSCHAFT (DE) | 2006-11-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100167931-A1 | HETEROCYCLICALLY SUBSTITUTED HETEROCYCLYLCARBOXYLIC ACID DERIVATIVES | HPD, HAAO, HCAR2 | MEN1 2048/4885KMT2A 2157/4885MAPK1 1273/4885 |
| US-20230062861-A1 | PPARg MODULATORS AND METHODS OF USE | PPARG, PPARA, PPARD | MEN1 4809/4885KMT2A 4267/4885MAPK1 1659/4885 |
| US-12606541-B2 | PPARg modulators and methods of use | PPARG, PPARA, PPARD | MEN1 4525/4885KMT2A 2698/4885MAPK1 1393/4885 |
| US-20090275589-A1 | Pyridazine Compound and Use Thereof | PLPBP, PNPO, PDXK | MEN1 3015/4885KMT2A 1894/4885MAPK1 1862/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.