Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.48 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.48 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.48 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.48 |
| ▸ | LIPE | Q05469 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MLYCD | O95822 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.41 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24339824 | 0.85 | MLYCD (0.56) | CHRNB2CHRNB4CHRNA3CHRNA4LIPE | |
| SCHEMBL22312033 | 0.81 | MLYCD (0.45) | MAPTALDH1A1TDP1MLYCDGPBAR1 | |
| SCHEMBL26644163 | 0.81 | KMT2A (0.46) | CHRNB2CHRNB4CHRNA3CHRNA4LIPE | |
| SCHEMBL26644166 | 0.81 | KMT2A (0.46) | CHRNB2CHRNB4CHRNA3CHRNA4LIPE | |
| SCHEMBL8586518 | 0.81 | KMT2A (0.46) | CHRNB2CHRNB4CHRNA3CHRNA4LIPE | |
| Hydrochloric Acid SCHEMBL29472254 | 0.80 | MLYCD (0.44) | MAPTALDH1A1TDP1MLYCDGPBAR1 | |
| Hydrochloric Acid SCHEMBL8010212 | 0.79 | KMT2A (0.44) | CHRNB2CHRNB4CHRNA3CHRNA4LIPE | |
| SCHEMBL28394955 | 0.78 | CHRNB2 (0.44) | CHRNB2CHRNB4CHRNA3CHRNA4LIPE | |
| SCHEMBL27641834 | 0.77 | CHRNB2 (0.39) | CHRNB2CHRNB4CHRNA3CHRNA4LIPE | |
| SCHEMBL11464199 | 0.76 | CHRNB2 (0.43) | CHRNB2CHRNB4CHRNA3CHRNA4LIPE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0648740-B1 | AMINO ACID AMIDE DERIVATIVE, AGROHORTICULTURAL BACTERICIDE, AND PRODUCTION PROCESS | KUMIAI CHEMICAL INDUSTRY CO (JP) | 1997-10-08 | — | — | EP | disclosed |
| US-5026711-A | Prevention and treatment of cardiovascular disorders and infections states; anxiolytic and anti-allergic agents | SANOFI (FR) | 1991-06-25 | — | — | US | disclosed |
| US-4981847-A | Tricyclic compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-01-01 | — | — | US | disclosed |