Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MARS2 | Q96GW9 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | BCL9 | O00512 | 1/20 | 0.38 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23747623 | 0.84 | NPC1 (0.49) | NPC1MAPTKMT2AMEN1MAPK1 | |
| SCHEMBL8772066 | 0.80 | UTS2R (0.47) | — | |
| SCHEMBL8772073 | 0.80 | ESR1 (0.40) | MAPTALDH1A1LMNACYP3A4CYP2C19 | |
| SCHEMBL7634742 | 0.79 | NPC1 (0.45) | NPC1MAPTKMT2AMEN1MAPK1 | |
| SCHEMBL8772074 | 0.79 | PABPC1 (0.51) | ALDH1A1SMN1; SMN2CYP3A4TSHR | |
| SCHEMBL8772060 | 0.79 | PABPC1 (0.51) | ALDH1A1SMN1; SMN2CYP3A4TSHR | |
| SCHEMBL28431736 | 0.78 | BCL9 (0.56) | NPC1MAPTKMT2ASMN1; SMN2BCL9 | |
| SCHEMBL13434048 | 0.77 | MAOB (0.41) | NPC1MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL27937254 | 0.77 | MAPT (0.53) | NPC1MAPTKMT2AMEN1MAPK1 | |
| SCHEMBL12237310 | 0.76 | FLT1 (0.43) | NPC1MAPTKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0529085-B1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE 3-CHLORO-1-PHENYL-1-PROPANOL AND DERIVATIVE THEREOF | DAICEL CHEM (JP) | 1997-08-20 | — | — | EP | disclosed |
| US-5457052-A | Treating a racemic mixture of the ester derivative of an unsaturated or saturated acid using a lipase from Pseudomonas or Aspergillus | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1995-10-10 | — | — | US | disclosed |
| EP-0529085-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE 3-CHLORO-1-PHENYL-1-PROPANOL AND DERIVATIVE THEREOF | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1993-03-03 | — | — | EP | disclosed |