Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.40 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8772066 | 0.87 | UTS2R (0.47) | UTS2R | |
| SCHEMBL8772074 | 0.85 | PABPC1 (0.51) | PABPC1APOBEC3AAPOBEC3GCYP3A4UTS2R | |
| SCHEMBL8772060 | 0.85 | PABPC1 (0.51) | PABPC1APOBEC3AAPOBEC3GCYP3A4UTS2R | |
| SCHEMBL14028741 | 0.81 | ESR1 (0.48) | ESR1ESR2PABPC1APOBEC3AAPOBEC3G | |
| SCHEMBL8772072 | 0.80 | NPC1 (0.46) | LMNACYP3A4MAPTCYP2C19ALDH1A1 | |
| SCHEMBL11108674 | 0.79 | ESR1 (0.42) | ESR1ESR2PABPC1APOBEC3AAPOBEC3G | |
| SCHEMBL9155085 | 0.79 | TAAR1 (0.46) | ESR1ESR2PABPC1APOBEC3AAPOBEC3G | |
| SCHEMBL27711499 | 0.78 | FFAR1 (0.42) | ESR1ESR2PABPC1APOBEC3AAPOBEC3G | |
| SCHEMBL13921515 | 0.75 | ESR1 (0.43) | ESR1ESR2PABPC1APOBEC3AAPOBEC3G | |
| SCHEMBL31599199 | 0.75 | PABPC1 (0.38) | PABPC1APOBEC3AAPOBEC3GSIGMAR1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0529085-B1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE 3-CHLORO-1-PHENYL-1-PROPANOL AND DERIVATIVE THEREOF | DAICEL CHEM (JP) | 1997-08-20 | — | — | EP | disclosed |
| US-5457052-A | Treating a racemic mixture of the ester derivative of an unsaturated or saturated acid using a lipase from Pseudomonas or Aspergillus | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1995-10-10 | — | — | US | disclosed |
| EP-0529085-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE 3-CHLORO-1-PHENYL-1-PROPANOL AND DERIVATIVE THEREOF | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1993-03-03 | — | — | EP | disclosed |