Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 5/20 | 0.41 |
| ▸ | TCF7L2 | Q9NQB0 | 5/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL874931 | 0.94 | KMT2A (0.48) | KMT2AMEN1GPR139ALDH1A1KDM4E | |
| SCHEMBL877234 | 0.93 | HTT (0.51) | KMT2AMEN1GPR139ALDH1A1KDM4E | |
| SCHEMBL874119 | 0.92 | GPR139 (0.47) | KMT2AMEN1GPR139ALDH1A1KDM4E | |
| SCHEMBL874217 | 0.92 | KMT2A (0.45) | KMT2AMEN1GPR139ALDH1A1KDM4E | |
| SCHEMBL874278 | 0.92 | KDM4E (0.43) | KMT2AMEN1GPR139ALDH1A1KDM4E | |
| SCHEMBL877266 | 0.92 | KMT2A (0.46) | KMT2AMEN1GPR139ALDH1A1KDM4E | |
| SCHEMBL877515 | 0.91 | KMT2A (0.47) | KMT2AMEN1GPR139ALDH1A1KDM4E | |
| SCHEMBL877079 | 0.89 | GPR139 (0.48) | KMT2AMEN1GPR139ALDH1A1KDM4E | |
| SCHEMBL873795 | 0.89 | GPR139 (0.48) | KMT2AMEN1GPR139ALDH1A1KDM4E | |
| SCHEMBL876636 | 0.85 | KMT2A (0.52) | KMT2AMEN1GPR139ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2619179-A1 | MATRIX METALLOPROTEINASE INHIBITORS | Ranbaxy Laboratories Limited (IN) | 2013-07-31 | — | — | EP | claimed |
| WO-2012038944-A1 | MATRIX METALLOPROTEINASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-03-29 | — | — | WO | claimed |
| EP-2619179-A1 | MATRIX METALLOPROTEINASE INHIBITORS | Ranbaxy Laboratories Limited (IN) | 2013-07-31 | — | — | EP | disclosed |
| WO-2012038944-A1 | MATRIX METALLOPROTEINASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-03-29 | — | — | WO | disclosed |