Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR139 | Q6DWJ6 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.43 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL874931 | 0.93 | KMT2A (0.48) | GPR139KMT2AMEN1ALDH1A1HSD17B10 | |
| SCHEMBL877224 | 0.92 | KMT2A (0.45) | GPR139KMT2AMEN1ALDH1A1HSD17B10 | |
| SCHEMBL877234 | 0.92 | HTT (0.51) | GPR139KMT2AMEN1ALDH1A1HSD17B10 | |
| SCHEMBL874217 | 0.91 | KMT2A (0.45) | GPR139KMT2AMEN1ALDH1A1HSD17B10 | |
| SCHEMBL877266 | 0.90 | KMT2A (0.46) | GPR139KMT2AMEN1ALDH1A1HSD17B10 | |
| SCHEMBL877733 | 0.90 | GPR139 (0.50) | GPR139KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL877515 | 0.89 | KMT2A (0.47) | GPR139KMT2AMEN1ALDH1A1HSD17B10 | |
| SCHEMBL874278 | 0.87 | KDM4E (0.43) | GPR139KMT2AMEN1ALDH1A1HSD17B10 | |
| SCHEMBL876636 | 0.83 | KMT2A (0.52) | GPR139KMT2AMEN1ALDH1A1HSD17B10 | |
| SCHEMBL877629 | 0.82 | MMP2 (0.45) | GPR139KMT2AMEN1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2619179-A1 | MATRIX METALLOPROTEINASE INHIBITORS | Ranbaxy Laboratories Limited (IN) | 2013-07-31 | — | — | EP | claimed |
| WO-2012038944-A1 | MATRIX METALLOPROTEINASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-03-29 | — | — | WO | claimed |
| EP-2619179-A1 | MATRIX METALLOPROTEINASE INHIBITORS | Ranbaxy Laboratories Limited (IN) | 2013-07-31 | — | — | EP | disclosed |
| WO-2012038944-A1 | MATRIX METALLOPROTEINASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-03-29 | — | — | WO | disclosed |