SCHEMBL8772247

SCHEMBL8772247

CN(C)c1ccc(C(c2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)c2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 2/20 0.46
TSHR P16473 5/20 0.42
MAPT P10636 3/20 0.42
CYP1A2 P05177 2/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
CYP3A4 P08684 1/20 0.42
MAPK1 P28482 1/20 0.42
PHLPP2 Q6ZVD8 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
CA2 P00918 4/20 0.42
CA1 P00915 2/20 0.42
ALDH1A1 P00352 6/20 0.42
LMNA P02545 2/20 0.42
GAA P10253 2/20 0.42
CYP2D6 P10635 1/20 0.42
SMN1; SMN2 Q16637 3/20 0.41
POLB P06746 1/20 0.41
TYR P14679 1/20 0.41
HSD17B10 Q99714 3/20 0.40
NQO1 P15559 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8772288 0.82 CA2 (0.61) TSHRMAPTCYP1A2L3MBTL1CYP3A4
SCHEMBL6240665 0.79 TSHR (0.51) TSHRMAPTCYP1A2CYP3A4TDP1
SCHEMBL28723066 0.79 TSHR (0.51) TSHRMAPTCYP1A2CYP3A4TDP1
SCHEMBL1597972 0.77 CYP1A2 (0.55) TSHRMAPTCYP1A2L3MBTL1CYP3A4
SCHEMBL8772264 0.77 CA2 (0.59) SLC2A1TSHRMAPTL3MBTL1CYP3A4
SCHEMBL10936815 0.76 SLC2A1 (0.54) SLC2A1TSHRMAPTCYP1A2L3MBTL1
SCHEMBL7508251 0.76 P4HB (0.53) TSHRMAPTMAPK1TDP1ALDH1A1
SCHEMBL1535843 0.76 CA2 (0.58) TSHRMAPTCYP1A2L3MBTL1CYP3A4
SCHEMBL61574 0.75 SLC2A1 (0.71) SLC2A1TSHRMAPTCYP1A2L3MBTL1
SCHEMBL9626237 0.75 SLC2A1 (0.71) SLC2A1TSHRMAPTCYP1A2L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0461621-B1 Image forming method CANON KK (JP) 1997-10-15 EP disclosed
EP-0412851-B1 Photosensitive member and multi-color image forming method CANON KK (JP) 1995-06-14 EP disclosed
EP-0363790-B1 Image forming method and image forming medium CANON KK (JP) 1995-05-31 EP disclosed
US-5409798-A Base layer containing polymerizable compound, photosensitive layer capable of peeling development containing different polymerizable compound, layer-forming polymer, photoinitiator, peeling support layer CANON KABUSHIKI KAISHA (JP) 1995-04-25 US disclosed
US-5393638-A Image forming method CANON KABUSHIKI KAISHA (JP) 1995-02-28 US disclosed
US-5374496-A Image forming method CANON KABUSHIKI KAISHA (JP) 1994-12-20 US disclosed
EP-0530674-A1 Plate blank, process for producing printing plate from plate blank, and printing method and apparatus using plate CANON KABUSHIKI KAISHA (JP) 1993-03-10 EP disclosed
US-5187041-A IMAGE FORMING METHOD AND IMAGE FORMING APPARATUS CANON KABUSHIKI KAISHA (JP) 1993-02-16 US disclosed
US-5171657-A Containing photopolymerizable monomer CANON KABUSHIKI KAISHA (JP) 1992-12-15 US disclosed
EP-0461621-A2 Image forming method CANON KABUSHIKI KAISHA (JP) 1991-12-18 EP disclosed
EP-0453125-A2 Image forming method and image forming apparatus CANON KABUSHIKI KAISHA (JP) 1991-10-23 EP disclosed
EP-0453317-A2 Image forming medium CANON KABUSHIKI KAISHA (JP) 1991-10-23 EP disclosed
US-5021321-A Photothermography; antifogging agents; contrast; lamination of matrix of silver salts and reducing agent and dispersed particles of dye, polymer precursor and photoinitiator CANON KABUSHIKI KAISHA (JP) 1991-06-04 US disclosed
EP-0412851-A2 Photosensitive member and multi-color image forming method CANON KABUSHIKI KAISHA (JP) 1991-02-13 EP disclosed
EP-0363790-A2 Image forming method and image forming medium CANON KABUSHIKI KAISHA (JP) 1990-04-18 EP disclosed