SCHEMBL8772254

SCHEMBL8772254

CC(C)(C)c1cc(Cc2cc(Cl)c(O)c(Cl)c2)cc(C(C)(C)C)c1O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.52
TSHR P16473 3/20 0.52
LMNA P02545 2/20 0.52
GAA P10253 2/20 0.52
SMN1; SMN2 Q16637 4/20 0.51
HIF1A Q16665 3/20 0.51
TP53 P04637 2/20 0.51
CYP2C9 P11712 2/20 0.51
CYP2C19 P33261 2/20 0.51
MAPK1 P28482 3/20 0.50
NPSR1 Q6W5P4 3/20 0.50
MEN1 O00255 2/20 0.50
CYP1A2 P05177 2/20 0.50
CYP3A4 P08684 2/20 0.50
BLM P54132 2/20 0.50
KMT2A Q03164 2/20 0.50
ATM Q13315 2/20 0.50
ALOX15 P16050 2/20 0.50
GMNN O75496 1/20 0.50
GABBR2 O75899 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL39559 0.88 ALDH1A1 (0.63) ALDH1A1TSHRLMNAGAASMN1; SMN2
SCHEMBL526641 0.86 ALDH1A1 (0.61) ALDH1A1TSHRLMNAGAASMN1; SMN2
Benzene SCHEMBL9807217 0.84 ALDH1A1 (0.59) ALDH1A1TSHRLMNAGAASMN1; SMN2
SCHEMBL9338699 0.82 ALDH1A1 (0.57) ALDH1A1TSHRLMNAGAASMN1; SMN2
Methylamine SCHEMBL27974836 0.82 ALDH1A1 (0.57) ALDH1A1TSHRLMNAGAASMN1; SMN2
SCHEMBL70208 0.81 HSD17B10 (0.55) ALDH1A1TSHRLMNASMN1; SMN2HIF1A
Butylated Hydroxytoluene SCHEMBL1000655 0.80 ALDH1A1 (0.75) ALDH1A1TSHRLMNAGAASMN1; SMN2
SCHEMBL14016140 0.80 ALDH1A1 (0.56) ALDH1A1TSHRLMNAGAASMN1; SMN2
SCHEMBL9413678 0.78 CYP2C9 (0.59) ALDH1A1TSHRLMNAGAASMN1; SMN2
SCHEMBL39543 0.78 HSPA5 (0.65) ALDH1A1TSHRLMNAGAASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0461621-B1 Image forming method CANON KK (JP) 1997-10-15 EP disclosed
EP-0412851-B1 Photosensitive member and multi-color image forming method CANON KK (JP) 1995-06-14 EP disclosed
EP-0363790-B1 Image forming method and image forming medium CANON KK (JP) 1995-05-31 EP disclosed
US-5409798-A Base layer containing polymerizable compound, photosensitive layer capable of peeling development containing different polymerizable compound, layer-forming polymer, photoinitiator, peeling support layer CANON KABUSHIKI KAISHA (JP) 1995-04-25 US disclosed
US-5393638-A Image forming method CANON KABUSHIKI KAISHA (JP) 1995-02-28 US disclosed
US-5374496-A Image forming method CANON KABUSHIKI KAISHA (JP) 1994-12-20 US disclosed
EP-0530674-A1 Plate blank, process for producing printing plate from plate blank, and printing method and apparatus using plate CANON KABUSHIKI KAISHA (JP) 1993-03-10 EP disclosed
US-5187041-A IMAGE FORMING METHOD AND IMAGE FORMING APPARATUS CANON KABUSHIKI KAISHA (JP) 1993-02-16 US disclosed
US-5171657-A Containing photopolymerizable monomer CANON KABUSHIKI KAISHA (JP) 1992-12-15 US disclosed
EP-0461621-A2 Image forming method CANON KABUSHIKI KAISHA (JP) 1991-12-18 EP disclosed
EP-0453125-A2 Image forming method and image forming apparatus CANON KABUSHIKI KAISHA (JP) 1991-10-23 EP disclosed
EP-0453317-A2 Image forming medium CANON KABUSHIKI KAISHA (JP) 1991-10-23 EP disclosed
US-5021321-A Photothermography; antifogging agents; contrast; lamination of matrix of silver salts and reducing agent and dispersed particles of dye, polymer precursor and photoinitiator CANON KABUSHIKI KAISHA (JP) 1991-06-04 US disclosed
EP-0412851-A2 Photosensitive member and multi-color image forming method CANON KABUSHIKI KAISHA (JP) 1991-02-13 EP disclosed
EP-0363790-A2 Image forming method and image forming medium CANON KABUSHIKI KAISHA (JP) 1990-04-18 EP disclosed