Butylated Hydroxytoluene

Butylated Hydroxytoluene

SCHEMBL1000655

CC(C)(C)c1cc(Cc2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)cc(C(C)(C)C)c1O.Cc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1

nearest known ligand 0.75

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.75
SMN1; SMN2 Q16637 4/20 0.75
CA2 P00918 2/20 0.75
POLB P06746 1/20 0.75
TYR P14679 1/20 0.75
HSPA5 P11021 2/20 0.66
HIF1A Q16665 5/20 0.63
CYP2C9 P11712 4/20 0.63
CYP2C19 P33261 4/20 0.63
CYP2D6 P10635 2/20 0.56
HSD17B10 Q99714 1/20 0.56
TSHR P16473 3/20 0.55
LMNA P02545 2/20 0.55
GAA P10253 1/20 0.55
MAPK1 P28482 3/20 0.53
MEN1 O00255 2/20 0.53
CYP1A2 P05177 2/20 0.53
CYP3A4 P08684 2/20 0.53
BLM P54132 2/20 0.53
KMT2A Q03164 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL39559 0.91 ALDH1A1 (0.63) ALDH1A1SMN1; SMN2CA2POLBTYR
SCHEMBL8047562 0.91 HSPA5 (0.83) ALDH1A1SMN1; SMN2CA2POLBTYR
SCHEMBL526641 0.89 ALDH1A1 (0.61) ALDH1A1SMN1; SMN2CA2POLBTYR
SCHEMBL8772330 0.89 HSPA5 (0.79) ALDH1A1SMN1; SMN2CA2POLBTYR
SCHEMBL14016140 0.88 ALDH1A1 (0.56) ALDH1A1SMN1; SMN2CA2POLBTYR
Benzene SCHEMBL9807217 0.87 ALDH1A1 (0.59) ALDH1A1SMN1; SMN2CA2POLBTYR
Butylated Hydroxytoluene SCHEMBL453824 0.87 SMN1; SMN2 (1.00) ALDH1A1SMN1; SMN2CA2POLBTYR
Butylated Hydroxytoluene SCHEMBL3950 0.87 SMN1; SMN2 (1.00) ALDH1A1SMN1; SMN2CA2POLBTYR
SCHEMBL5570178 0.86 ALDH1A1 (0.55) ALDH1A1SMN1; SMN2CA2POLBTYR
SCHEMBL8772331 0.86 ALDH1A1 (0.54) ALDH1A1SMN1; SMN2CA2POLBTYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111548622-B PA/PE (polyamide/polyethylene) blend alloy with low water absorption and high dimensional stability and preparation method thereof 宁波坚锋新材料有限公司 2023-02-14 CN disclosed
CN-115160755-A Transparent polycarbonate recycled material and preparation method thereof 宁波坚锋新材料有限公司 2022-10-11 CN disclosed
CN-115160771-A Isomeric micro-crosslinked regenerated nylon and preparation method thereof 宁波坚锋新材料有限公司 2022-10-11 CN disclosed
US-7863229-B2 Lubricating compositions EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2011-01-04 US disclosed
EP-1969607-B1 A COMPOSITION OF INSULATING FLUID AND PROCESS FOR THE PREPARATION THEREOF COUNCIL SCIENT IND RES (IN) 2010-03-10 EP disclosed
US-20080026962-A1 Lubricant compositions having improved low temperature properties POIRIER MARC-ANDRE 2008-01-31 US disclosed
US-20070298987-A1 Lubricating compositions EXXONMOBIL RESEARCH AND ENGINEERING COMPANY 2007-12-27 US disclosed
US-4000112-A POLYOLEFINS, TURBINE OILS CIBA-GEIGY CORPORATION (US) 1976-12-28 US disclosed