SCHEMBL8772256

SCHEMBL8772256

Cc1cc(Cc2ccc(O)c(C(C)(C)C)c2)c(O)c(C(C)(C)C)c1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSPA5 P11021 2/20 0.68
CYP2C9 P11712 6/20 0.66
CYP2C19 P33261 5/20 0.66
HIF1A Q16665 5/20 0.66
SMN1; SMN2 Q16637 4/20 0.66
HSD17B10 Q99714 3/20 0.59
CYP2D6 P10635 3/20 0.59
ALDH1A1 P00352 7/20 0.50
TYR P14679 2/20 0.50
CA2 P00918 1/20 0.50
POLB P06746 1/20 0.50
AMY1A P0DUB6 1/20 0.46
LMNA P02545 3/20 0.43
ALOX15 P16050 3/20 0.43
NR1I2 O75469 1/20 0.43
MIF P14174 1/20 0.43
HTT P42858 1/20 0.43
NFE2L2 Q16236 1/20 0.43
MAPT P10636 3/20 0.41
ESR1 P03372 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8772330 0.85 HSPA5 (0.79) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL8377432 0.84 HSPA5 (0.72) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL699786 0.83 HSPA5 (0.51) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL9950640 0.82 HSPA5 (0.79) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL12309158 0.82 HSPA5 (0.79) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL12323446 0.82 HSPA5 (0.68) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL29351672 0.82 HSPA5 (1.00) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL29415372 0.82 HSPA5 (1.00) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL34162 0.82 HSPA5 (1.00) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
Butylated Hydroxytoluene SCHEMBL28247346 0.81 ALDH1A1 (0.58) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0461621-B1 Image forming method CANON KK (JP) 1997-10-15 EP disclosed
EP-0412851-B1 Photosensitive member and multi-color image forming method CANON KK (JP) 1995-06-14 EP disclosed
EP-0363790-B1 Image forming method and image forming medium CANON KK (JP) 1995-05-31 EP disclosed
US-5393638-A Image forming method CANON KABUSHIKI KAISHA (JP) 1995-02-28 US disclosed
US-5374496-A Image forming method CANON KABUSHIKI KAISHA (JP) 1994-12-20 US disclosed
US-5187041-A IMAGE FORMING METHOD AND IMAGE FORMING APPARATUS CANON KABUSHIKI KAISHA (JP) 1993-02-16 US disclosed
US-5171657-A Containing photopolymerizable monomer CANON KABUSHIKI KAISHA (JP) 1992-12-15 US disclosed
EP-0461621-A2 Image forming method CANON KABUSHIKI KAISHA (JP) 1991-12-18 EP disclosed
EP-0453125-A2 Image forming method and image forming apparatus CANON KABUSHIKI KAISHA (JP) 1991-10-23 EP disclosed
US-5021321-A Photothermography; antifogging agents; contrast; lamination of matrix of silver salts and reducing agent and dispersed particles of dye, polymer precursor and photoinitiator CANON KABUSHIKI KAISHA (JP) 1991-06-04 US disclosed
EP-0412851-A2 Photosensitive member and multi-color image forming method CANON KABUSHIKI KAISHA (JP) 1991-02-13 EP disclosed
EP-0363790-A2 Image forming method and image forming medium CANON KABUSHIKI KAISHA (JP) 1990-04-18 EP disclosed