Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR139 | Q6DWJ6 | 13/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 3/20 | 0.37 |
| ▸ | MMP9 | P14780 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL876799 | 0.93 | GPR139 (0.51) | GPR139NPSR1ALDH1A1USP2GAA | |
| SCHEMBL874810 | 0.93 | GPR139 (0.52) | GPR139NPSR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL874163 | 0.89 | GPR139 (0.45) | GPR139ALDH1A1SMN1; SMN2HSD17B10MMP2 | |
| SCHEMBL876956 | 0.89 | GPR139 (0.43) | GPR139SMN1; SMN2MMP2MMP9 | |
| SCHEMBL873794 | 0.85 | GPR139 (0.42) | GPR139NPSR1ALDH1A1SMN1; SMN2MMP2 | |
| SCHEMBL876684 | 0.85 | GPR139 (0.52) | GPR139NPSR1ALDH1A1SMN1; SMN2USP2 | |
| SCHEMBL878345 | 0.85 | GPR139 (0.52) | GPR139NPSR1ALDH1A1SMN1; SMN2USP2 | |
| SCHEMBL876807 | 0.84 | GPR139 (0.42) | GPR139NPSR1ALDH1A1SMN1; SMN2MMP2 | |
| SCHEMBL874812 | 0.84 | GPR139 (0.46) | GPR139SMN1; SMN2MMP2MMP9 | |
| SCHEMBL873796 | 0.83 | GPR139 (0.48) | GPR139NPSR1ALDH1A1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2619179-A1 | MATRIX METALLOPROTEINASE INHIBITORS | Ranbaxy Laboratories Limited (IN) | 2013-07-31 | — | — | EP | disclosed |
| WO-2012038944-A1 | MATRIX METALLOPROTEINASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-03-29 | — | — | WO | disclosed |