Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR139 | Q6DWJ6 | 9/20 | 0.42 |
| ▸ | MMP1 | P03956 | 3/20 | 0.39 |
| ▸ | MMP2 | P08253 | 3/20 | 0.39 |
| ▸ | MMP3 | P08254 | 3/20 | 0.39 |
| ▸ | MMP9 | P14780 | 3/20 | 0.39 |
| ▸ | MMP13 | P45452 | 3/20 | 0.39 |
| ▸ | OXTR | P30559 | 6/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | AVPR2 | P30518 | 3/20 | 0.35 |
| ▸ | AVPR1A | P37288 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL877235 | 0.90 | MMP2 (0.46) | GPR139MMP1MMP2MMP3MMP9 | |
| SCHEMBL877886 | 0.90 | MMP2 (0.46) | GPR139MMP1MMP2MMP3MMP9 | |
| SCHEMBL876621 | 0.90 | GPR139 (0.40) | GPR139MMP1MMP2MMP3MMP9 | |
| SCHEMBL874810 | 0.90 | GPR139 (0.52) | GPR139NPSR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL876807 | 0.86 | GPR139 (0.42) | GPR139MMP1MMP2MMP3MMP9 | |
| SCHEMBL877229 | 0.85 | GPR139 (0.51) | GPR139MMP2MMP9NPSR1ALDH1A1 | |
| SCHEMBL877287 | 0.82 | MMP1 (0.47) | GPR139MMP1MMP2MMP3MMP9 | |
| SCHEMBL877837 | 0.82 | MMP1 (0.47) | GPR139MMP1MMP2MMP3MMP9 | |
| SCHEMBL877887 | 0.81 | MMP2 (0.42) | GPR139MMP1MMP2MMP3MMP9 | |
| SCHEMBL878345 | 0.81 | GPR139 (0.52) | GPR139MMP1MMP2MMP3MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2619179-A1 | MATRIX METALLOPROTEINASE INHIBITORS | Ranbaxy Laboratories Limited (IN) | 2013-07-31 | — | — | EP | claimed |
| WO-2012038944-A1 | MATRIX METALLOPROTEINASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-03-29 | — | — | WO | claimed |
| EP-2619179-A1 | MATRIX METALLOPROTEINASE INHIBITORS | Ranbaxy Laboratories Limited (IN) | 2013-07-31 | — | — | EP | disclosed |
| WO-2012038944-A1 | MATRIX METALLOPROTEINASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-03-29 | — | — | WO | disclosed |