Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19452725 | 0.90 | HDAC1 (0.53) | TDP1ALDH1A1TSHRHSD17B10KMT2A | |
| SCHEMBL29086538 | 0.83 | TDP1 (0.73) | TDP1ALDH1A1KEAP1KMT2AL3MBTL1 | |
| SCHEMBL1380801 | 0.82 | TDP1 (0.61) | TDP1ALDH1A1KEAP1KMT2AL3MBTL1 | |
| SCHEMBL491370 | 0.82 | ALDH1A1 (0.55) | TDP1ALDH1A1TSHRHSD17B10KMT2A | |
| SCHEMBL7697901 | 0.81 | MAPT (0.51) | TDP1KMT2AMAPTHDAC2HDAC8 | |
| SCHEMBL27839288 | 0.80 | TDP1 (0.63) | TDP1ALDH1A1KEAP1KMT2AL3MBTL1 | |
| SCHEMBL8823344 | 0.78 | TDP1 (0.51) | TDP1ALDH1A1KEAP1KMT2AL3MBTL1 | |
| SCHEMBL1838210 | 0.77 | TDP1 (0.63) | TDP1ALDH1A1KEAP1KMT2AL3MBTL1 | |
| Methyl 3-Phenylpropanoate SCHEMBL168711 | 0.76 | TDP1 (0.68) | TDP1ALDH1A1KEAP1KMT2AHTT | |
| SCHEMBL1739439 | 0.75 | TDP1 (0.73) | TDP1ALDH1A1KEAP1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0799288-A1 | INTUMESCENT PUTTY | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1997-10-08 | — | — | EP | disclosed |
| WO-1996020987-A1 | INTUMESCENT PUTTY | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-07-11 | — | — | WO | disclosed |