SCHEMBL8772390

SCHEMBL8772390

Oc1cc2c(cc1Cl)C(c1ccccc1)c1cc(Cl)c(O)cc1O2

nearest known ligand 0.49

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.49
KMT2A Q03164 3/20 0.49
GAA P10253 2/20 0.49
CASP6 P55212 1/20 0.49
DRD1 P21728 9/20 0.42
DRD2 P14416 8/20 0.42
ALDH1A1 P00352 2/20 0.40
KDM4E B2RXH2 1/20 0.40
LMNA P02545 1/20 0.40
MAPT P10636 1/20 0.40
HTT P42858 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
TSHR P16473 1/20 0.40
MAPK1 P28482 1/20 0.40
ESR2 Q92731 1/20 0.40
HSD17B10 Q99714 1/20 0.40
DRD5 P21918 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17977152 0.83 MEN1 (0.40) MEN1KMT2AGAACASP6DRD1
SCHEMBL8772391 0.83 MEN1 (0.43) MEN1KMT2AGAACASP6DRD1
SCHEMBL26064841 0.80 MEN1 (0.49) MEN1KMT2AGAACASP6DRD1
SCHEMBL621657 0.79 CYP2C9 (0.61) MEN1KMT2AGAACASP6DRD1
SCHEMBL29352425 0.79 CYP2C9 (0.61) MEN1KMT2AGAACASP6DRD1
SCHEMBL31214032 0.79 CYP2C9 (0.61) MEN1KMT2AGAACASP6DRD1
SCHEMBL30712035 0.77 MEN1 (0.47) MEN1KMT2AGAACASP6DRD1
SCHEMBL30712039 0.77 MEN1 (0.47) MEN1KMT2AGAACASP6DRD1
SCHEMBL19851151 0.74 MEN1 (0.64) MEN1KMT2AGAAALDH1A1MAPT
SCHEMBL5030661 0.74 ALDH1A1 (0.56) MEN1KMT2AGAADRD1DRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0461621-B1 Image forming method CANON KK (JP) 1997-10-15 EP disclosed
EP-0363790-B1 Image forming method and image forming medium CANON KK (JP) 1995-05-31 EP disclosed
US-5393638-A Image forming method CANON KABUSHIKI KAISHA (JP) 1995-02-28 US disclosed
US-5374496-A Image forming method CANON KABUSHIKI KAISHA (JP) 1994-12-20 US disclosed
US-5187041-A IMAGE FORMING METHOD AND IMAGE FORMING APPARATUS CANON KABUSHIKI KAISHA (JP) 1993-02-16 US disclosed
US-5171657-A Containing photopolymerizable monomer CANON KABUSHIKI KAISHA (JP) 1992-12-15 US disclosed
EP-0461621-A2 Image forming method CANON KABUSHIKI KAISHA (JP) 1991-12-18 EP disclosed
EP-0453125-A2 Image forming method and image forming apparatus CANON KABUSHIKI KAISHA (JP) 1991-10-23 EP disclosed
US-5021321-A Photothermography; antifogging agents; contrast; lamination of matrix of silver salts and reducing agent and dispersed particles of dye, polymer precursor and photoinitiator CANON KABUSHIKI KAISHA (JP) 1991-06-04 US disclosed
EP-0363790-A2 Image forming method and image forming medium CANON KABUSHIKI KAISHA (JP) 1990-04-18 EP disclosed