SCHEMBL8772391

SCHEMBL8772391

CCN(CC)c1ccc2c(c1)Oc1cc(O)c(Cl)cc1C2c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 7/20 0.43
KMT2A Q03164 7/20 0.43
GAA P10253 7/20 0.43
SMN1; SMN2 Q16637 3/20 0.43
HTT P42858 3/20 0.43
NPC1 O15118 2/20 0.43
CYP3A4 P08684 2/20 0.43
NPSR1 Q6W5P4 2/20 0.43
TSHR P16473 2/20 0.43
USP2 O75604 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP2D6 P10635 1/20 0.43
CYP2C9 P11712 1/20 0.43
CASP1 P29466 1/20 0.43
CYP2C19 P33261 1/20 0.43
BRCA1 P38398 1/20 0.43
CASP7 P55210 1/20 0.43
HBB P68871 1/20 0.43
CASP6 P55212 1/20 0.40
MAPT P10636 8/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL82135 0.87 MEN1 (0.52) MEN1KMT2AGAASMN1; SMN2HTT
SCHEMBL8772390 0.83 MEN1 (0.49) MEN1KMT2AGAASMN1; SMN2HTT
SCHEMBL9659502 0.82 MEN1 (0.47) MEN1KMT2AGAASMN1; SMN2HTT
SCHEMBL11520111 0.79 MEN1 (0.48) MEN1KMT2AGAASMN1; SMN2HTT
SCHEMBL3907415 0.78 MEN1 (0.44) MEN1KMT2AGAASMN1; SMN2HTT
SCHEMBL21396807 0.76 CYP3A4 (0.45) MEN1KMT2AGAASMN1; SMN2HTT
SCHEMBL8778047 0.75 NPSR1 (0.46) MEN1KMT2AGAASMN1; SMN2HTT
SCHEMBL11289610 0.75 MEN1 (0.46) MEN1KMT2AGAASMN1; SMN2HTT
SCHEMBL18213659 0.75 KMT2A (0.42) MEN1KMT2AGAASMN1; SMN2HTT
SCHEMBL21168242 0.74 CYP3A4 (0.42) MEN1KMT2AGAASMN1; SMN2HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0461621-B1 Image forming method CANON KK (JP) 1997-10-15 EP disclosed
EP-0412851-B1 Photosensitive member and multi-color image forming method CANON KK (JP) 1995-06-14 EP disclosed
EP-0363790-B1 Image forming method and image forming medium CANON KK (JP) 1995-05-31 EP disclosed
US-5393638-A Image forming method CANON KABUSHIKI KAISHA (JP) 1995-02-28 US disclosed
US-5374496-A Image forming method CANON KABUSHIKI KAISHA (JP) 1994-12-20 US disclosed
US-5187041-A IMAGE FORMING METHOD AND IMAGE FORMING APPARATUS CANON KABUSHIKI KAISHA (JP) 1993-02-16 US disclosed
US-5171657-A Containing photopolymerizable monomer CANON KABUSHIKI KAISHA (JP) 1992-12-15 US disclosed
EP-0461621-A2 Image forming method CANON KABUSHIKI KAISHA (JP) 1991-12-18 EP disclosed
EP-0453125-A2 Image forming method and image forming apparatus CANON KABUSHIKI KAISHA (JP) 1991-10-23 EP disclosed
US-5021321-A Photothermography; antifogging agents; contrast; lamination of matrix of silver salts and reducing agent and dispersed particles of dye, polymer precursor and photoinitiator CANON KABUSHIKI KAISHA (JP) 1991-06-04 US disclosed
EP-0412851-A2 Photosensitive member and multi-color image forming method CANON KABUSHIKI KAISHA (JP) 1991-02-13 EP disclosed
EP-0363790-A2 Image forming method and image forming medium CANON KABUSHIKI KAISHA (JP) 1990-04-18 EP disclosed