SCHEMBL8772437

SCHEMBL8772437

Cc1cc(-c2cccc(C)c2-c2cc(C)c(O)c(C(C)(C)C)c2)cc(C(C)(C)C)c1O

nearest known ligand 0.61

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.61
CYP2C9 P11712 1/20 0.61
CYP2C19 P33261 1/20 0.61
GABRA1 P14867 1/20 0.51
GABRB2 P47870 1/20 0.51
CA2 P00918 4/20 0.44
CA1 P00915 2/20 0.44
PTPN1 P18031 1/20 0.40
ALDH1A1 P00352 2/20 0.39
POLB P06746 1/20 0.39
TYR P14679 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
PTGS1 P23219 4/20 0.39
PTGS2 P35354 4/20 0.39
PTPN5 P54829 1/20 0.37
SCN2A Q99250 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6240671 0.94 CA2 (0.52) CYP1A2CYP2C9CYP2C19GABRA1GABRB2
SCHEMBL29015802 0.85 CYP1A2 (0.71) CYP1A2CYP2C9CYP2C19GABRA1GABRB2
SCHEMBL2026463 0.85 CA1 (0.50) CA2CA1ALDH1A1PTGS1PTGS2
SCHEMBL29142801 0.83 CA2 (0.59) CYP1A2CYP2C9CYP2C19GABRA1GABRB2
SCHEMBL9295085 0.80 CA2 (0.47) CYP1A2CYP2C9CYP2C19GABRA1GABRB2
SCHEMBL30875145 0.79 CA2 (0.64) CYP1A2CYP2C9CYP2C19GABRA1GABRB2
SCHEMBL11427045 0.78 CA2 (0.57) CYP1A2CYP2C9CYP2C19GABRA1GABRB2
SCHEMBL16581433 0.78 CYP1A2 (0.78) CYP1A2CYP2C9CYP2C19GABRA1GABRB2
SCHEMBL15135001 0.78 ALDH1A1 (0.44) CYP1A2CYP2C9CYP2C19GABRA1GABRB2
SCHEMBL10569679 0.78 CA2 (0.52) CYP1A2CYP2C9CYP2C19GABRA1GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0461621-B1 Image forming method CANON KK (JP) 1997-10-15 EP disclosed
EP-0412851-B1 Photosensitive member and multi-color image forming method CANON KK (JP) 1995-06-14 EP disclosed
EP-0363790-B1 Image forming method and image forming medium CANON KK (JP) 1995-05-31 EP disclosed
US-5393638-A Image forming method CANON KABUSHIKI KAISHA (JP) 1995-02-28 US disclosed
US-5374496-A Image forming method CANON KABUSHIKI KAISHA (JP) 1994-12-20 US disclosed
US-5187041-A IMAGE FORMING METHOD AND IMAGE FORMING APPARATUS CANON KABUSHIKI KAISHA (JP) 1993-02-16 US disclosed
US-5171657-A Containing photopolymerizable monomer CANON KABUSHIKI KAISHA (JP) 1992-12-15 US disclosed
EP-0461621-A2 Image forming method CANON KABUSHIKI KAISHA (JP) 1991-12-18 EP disclosed
EP-0453125-A2 Image forming method and image forming apparatus CANON KABUSHIKI KAISHA (JP) 1991-10-23 EP disclosed
EP-0412851-A2 Photosensitive member and multi-color image forming method CANON KABUSHIKI KAISHA (JP) 1991-02-13 EP disclosed