Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | GSK3B | P49841 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | DAO | P14920 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7132233 | 0.91 | HDAC1 (0.47) | ALDH1A1GAAKDM4EPOLBCTDSP1 | |
| SCHEMBL5757987 | 0.86 | CES2 (0.65) | ALDH1A1KDM4EMAPTCES2CES1 | |
| SCHEMBL1854 | 0.86 | CES2 (0.65) | ALDH1A1KDM4EMAPTCES2CES1 | |
| SCHEMBL1330271 | 0.86 | CES2 (0.65) | ALDH1A1KDM4EMAPTCES2CES1 | |
| Ammonia Solution, Strong SCHEMBL28864885 | 0.84 | CES2 (0.62) | ALDH1A1KDM4EMAPTCES2CES1 | |
| Hydrochloric Acid SCHEMBL5565187 | 0.84 | CES2 (0.62) | ALDH1A1KDM4EMAPTCES2CES1 | |
| Bromide SCHEMBL28583978 | 0.84 | CES2 (0.62) | ALDH1A1KDM4EMAPTCES2CES1 | |
| SCHEMBL7702725 | 0.83 | HDAC1 (0.60) | ALDH1A1NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL5751057 | 0.83 | TSHR (0.74) | ALDH1A1GAAKDM4EPOLBCTDSP1 | |
| SCHEMBL7349867 | 0.81 | CES2 (0.59) | ALDH1A1KDM4EMAPTCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639559-B1 | Preparation of 1,2-diacyl-2-(t-alkyl)hydrazines | ROHM & HAAS (US) | 1997-10-15 | — | — | EP | claimed |
| EP-0639559-A1 | Preparation of 1,2-diacyl-2-(t-alkyl)hydrazines | ROHM AND HAAS COMPANY (US) | 1995-02-22 | — | — | EP | claimed |
| CN-1050599-C | Preparation of 1,2-diacyl-2-(T-alkyl) hydrazines | ROHM & HAAS (US) | 2000-03-22 | — | — | CN | disclosed |
| EP-0639559-B1 | Preparation of 1,2-diacyl-2-(t-alkyl)hydrazines | ROHM & HAAS (US) | 1997-10-15 | — | — | EP | disclosed |
| CN-1109049-A | Preparation of 1,2-diacyl-2-(T-alkyl) hydrazines | ROHM & HAAS (US) | 1995-09-27 | — | — | CN | disclosed |
| EP-0639559-A1 | Preparation of 1,2-diacyl-2-(t-alkyl)hydrazines | ROHM AND HAAS COMPANY (US) | 1995-02-22 | — | — | EP | disclosed |