SCHEMBL8772468

SCHEMBL8772468

O=C(CCCCCCCCCCCCCCCCCO)OCC(CO)(CO)CO

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 1/20 0.41
FFAR1 O14842 1/20 0.41
FFAR4 Q5NUL3 1/20 0.41
DGKA P23743 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.38
ALDH1A1 P00352 1/20 0.38
TP53 P04637 1/20 0.38
CYP3A4 P08684 1/20 0.38
MAPK1 P28482 1/20 0.38
HIF1A Q16665 1/20 0.38
PAM P19021 2/20 0.36
KDM4E B2RXH2 2/20 0.36
DUSP3 P51452 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
LMNA P02545 1/20 0.36
GAA P10253 1/20 0.34
CYP4F2 P78329 1/20 0.34
CYP4A11 Q02928 1/20 0.34
TSHR P16473 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9579855 1.00 GPR84 (0.41) GPR84FFAR1FFAR4DGKASMN1; SMN2
SCHEMBL8772488 0.98 GPR84 (0.40) GPR84FFAR1FFAR4DGKASMN1; SMN2
SCHEMBL16623976 0.92 GPR84 (0.44) GPR84FFAR1FFAR4DGKASMN1; SMN2
SCHEMBL17705378 0.92 GPR84 (0.44) GPR84FFAR1FFAR4DGKASMN1; SMN2
SCHEMBL1278334 0.92 GPR84 (0.44) GPR84FFAR1FFAR4DGKASMN1; SMN2
Cetyl Alcohol SCHEMBL4391783 0.91 DGKA (0.55) DGKAALDH1A1MAPK1PAMKDM4E
SCHEMBL29988015 0.89 DGKA (0.43) GPR84FFAR1FFAR4DGKASMN1; SMN2
SCHEMBL11514839 0.87 CYP3A4 (0.43) DGKASMN1; SMN2ALDH1A1TP53CYP3A4
SCHEMBL9994012 0.86 TSHR (0.46) GPR84FFAR1FFAR4ALDH1A1PAM
SCHEMBL14489501 0.86 GPR84 (0.40) GPR84FFAR1FFAR4DGKASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0605831-B1 Filler-containing resin composition and stretched films using same MITSUBISHI CHEM CORP (JP) 1997-10-15 EP disclosed
EP-0516351-B1 Flame-retardant polybutylene terephthalate resin composition POLYPLASTICS CO (JP) 1997-10-15 EP disclosed
US-5385972-A For waterproofing films having good elastic recovery, strength and gas permeability MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1995-01-31 US disclosed
EP-0605831-A1 Filler-containing resin composition and stretched films using same MITSUBISHI CHEMICAL CORPORATION (JP) 1994-07-13 EP disclosed
US-5258434-A Halogenated phenoxy compound, antimony pentaoxide, alkali metal oxide, fatty acid ester, and filler; electronics POLYPLASTICS CO., LTD. (JP) 1993-11-02 US disclosed
EP-0516351-A2 Flame-retardant polybutylene terephthalate resin composition POLYPLASTICS CO. LTD. (JP) 1992-12-02 EP disclosed
US-5126391-A Ethylene copolymer with olefin or diolefin, with glyceride of hydroxy aliphatic acid additive, tear strength MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1992-06-30 US disclosed
EP-0459142-A2 Filler-containing stretched film MITSUBISHI CHEMICAL CORPORATION (JP) 1991-12-04 EP disclosed