Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 6/20 | 0.62 |
| ▸ | BCHE | P06276 | 7/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31232300 | 0.97 | BCHE (0.65) | BCHEACHE | |
| Bromide SCHEMBL7928519 | 0.95 | BCHE (0.67) | BCHEACHE | |
| SCHEMBL5393053 | 0.90 | BCHE (0.70) | BCHEACHE | |
| SCHEMBL7046057 | 0.87 | BCHE (0.75) | BCHEACHE | |
| Bromide SCHEMBL7919286 | 0.87 | BCHE (0.71) | BCHEACHE | |
| SCHEMBL30105291 | 0.87 | BCHE (0.75) | BCHEACHE | |
| SCHEMBL2407838 | 0.87 | BCHE (0.75) | BCHEACHE | |
| SCHEMBL7045560 | 0.87 | BCHE (0.75) | BCHEACHE | |
| Bromide SCHEMBL2401340 | 0.85 | BCHE (0.76) | BCHEACHE | |
| Bromide SCHEMBL7927418 | 0.85 | BCHE (0.76) | BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0580078-B1 | Hydrophilic groups containing poly(vinylamine) derivatives, process for their manufacture and use thereof as pharmaceutical compounds, substrates for active substances and foodstuff ingredients | HOECHST AG (DE) | 1997-10-15 | — | — | EP | disclosed |
| US-5430110-A | Polyvinylamine derivatives having hydrophilic centers, processes for their preparation and the use of the compounds as a medicament, active compound carrier and foodstuff auxiliary | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-07-04 | — | — | US | disclosed |
| EP-0580078-A1 | Hydrophilic groups containing poly(vinylamine) derivatives, process for their manufacture and use thereof as pharmaceutical compounds, substrates for active substances and foodstuff ingredients | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-01-26 | — | — | EP | disclosed |