SCHEMBL8772638

SCHEMBL8772638

CCCCN(CCCC)C(=S)SCCC

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.65
ALDH2 P05091 3/20 0.65
MGLL Q99685 4/20 0.47
CA12 O43570 6/20 0.45
CA1 P00915 6/20 0.45
CA9 Q16790 6/20 0.45
CA2 P00918 4/20 0.45
PKM P14618 3/20 0.44
PHGDH O43175 3/20 0.41
MMP1 P03956 1/20 0.36
MMP2 P08253 1/20 0.36
MMP3 P08254 1/20 0.36
MMP8 P22894 1/20 0.36
CYP3A4 P08684 2/20 0.34
CYP1A2 P05177 2/20 0.34
CYP2C9 P11712 2/20 0.34
CYP2C19 P33261 2/20 0.34
PLIN1 O60240 1/20 0.34
GMNN O75496 1/20 0.34
TRPA1 O75762 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL980821 0.93 ALDH1A1 (0.68) ALDH1A1ALDH2MGLLCA12CA1
SCHEMBL11718644 0.92 MGLL (0.58) ALDH1A1ALDH2MGLLCA12CA1
SCHEMBL11295720 0.92 MGLL (0.58) ALDH1A1ALDH2MGLLCA12CA1
SCHEMBL11011503 0.91 ALDH1A1 (0.65) ALDH1A1ALDH2MGLLCA12CA1
SCHEMBL1902072 0.91 ALDH1A1 (0.65) ALDH1A1ALDH2MGLLCA12CA1
SCHEMBL10802513 0.89 ALDH1A1 (0.63) ALDH1A1ALDH2MGLLCA12CA1
SCHEMBL3166492 0.88 ALDH1A1 (0.61) ALDH1A1ALDH2MGLLCA12CA1
SCHEMBL21221384 0.87 ALDH1A1 (0.59) ALDH1A1ALDH2MGLLCA12CA1
SCHEMBL11720450 0.86 CA12 (0.48) ALDH1A1ALDH2MGLLCA12CA1
SCHEMBL14507928 0.86 ALDH1A1 (0.59) ALDH1A1ALDH2MGLLCA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1045309-C Sulfurized aqueous machining fluid composition CINCINNATI MILACRON INC (US) 1999-09-29 CN disclosed
EP-0656415-B1 Sulfurized aqueous machining fluid composition CINCINNATI MILACRON INC (US) 1997-10-08 EP disclosed
CN-1120067-A Sulfurized aqueous machining fluid composition CINCINNATI MILACRON INC (US) 1996-04-10 CN disclosed
EP-0656415-A1 Sulfurized aqueous machining fluid composition CINCINNATI MILACRON INC. (US) 1995-06-07 EP disclosed
US-5391310-A Mixture of water and an organosulfur compound CINCINNATI MILACRON INC. (US) 1995-02-21 US disclosed