Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.54 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.46 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8772722 | 0.91 | TNKS2 (0.51) | TNKS2HTR2AHTR2CHTR2BPPARG | |
| SCHEMBL22609994 | 0.89 | TNKS2 (0.62) | TNKS2HTR2AHTR2CHTR2B | |
| SCHEMBL12338366 | 0.86 | HTR2A (0.50) | TNKS2HTR2AHTR2CHTR2B | |
| SCHEMBL9124419 | 0.86 | S1PR2 (0.48) | S1PR2S1PR1S1PR3LPAR2 | |
| SCHEMBL19194199 | 0.84 | TNKS2 (0.47) | TNKS2HTR2AHTR2CHTR2B | |
| SCHEMBL27570422 | 0.84 | TNKS2 (0.53) | TNKS2HTR2AHTR2CHTR2BPPARG | |
| SCHEMBL20436811 | 0.83 | S1PR2 (0.46) | S1PR2S1PR1S1PR3LPAR2 | |
| SCHEMBL8772750 | 0.83 | HTR2A (0.47) | HTR2AHTR2CHTR2B | |
| SCHEMBL15270668 | 0.83 | THRA (0.48) | S1PR1 | |
| SCHEMBL2007007 | 0.80 | TNKS2 (0.68) | TNKS2HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0801071-A1 | LEWIS X DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1997-10-15 | — | — | EP | disclosed |