Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | ESR1 | P03372 | 2/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.50 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.50 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.50 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.50 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.50 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL7387505 | 0.97 | OPRM1 (0.58) | OPRM1MEN1CYP2C9KMT2AESR1 | |
| SCHEMBL827795 | 0.94 | OPRM1 (0.61) | OPRM1MEN1CYP2C9KMT2AESR1 | |
| SCHEMBL30877902 | 0.92 | ESR1 (0.58) | OPRM1MEN1CYP2C9KMT2AESR1 | |
| SCHEMBL54982 | 0.92 | ESR1 (0.58) | OPRM1MEN1CYP2C9KMT2AESR1 | |
| SCHEMBL28378542 | 0.92 | ESR1 (0.58) | OPRM1MEN1CYP2C9KMT2AESR1 | |
| SCHEMBL24157288 | 0.92 | ESR1 (0.58) | OPRM1MEN1CYP2C9KMT2AESR1 | |
| SCHEMBL30877914 | 0.92 | ESR1 (0.58) | OPRM1MEN1CYP2C9KMT2AESR1 | |
| SCHEMBL30078304 | 0.92 | ESR1 (0.58) | OPRM1MEN1CYP2C9KMT2AESR1 | |
| SCHEMBL1515174 | 0.89 | ESR1 (0.56) | OPRM1MEN1CYP2C9KMT2AESR1 | |
| Hydrogen Peroxide SCHEMBL2349581 | 0.89 | ESR1 (0.62) | OPRM1MEN1CYP2C9KMT2AESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0031708-B1 | CEPHALOSPORIN DERIVATIVES, PROCESSES FOR THEIR MANUFACTURE, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND INTERMEDIATES THEREFOR | ICI PHARMA (FR) | 1984-06-13 | — | — | EP | claimed |
| EP-0075434-A2 | Cephalosporins, their preparation and their pharmaceutical compositions | ICI PHARMA (FR) | 1983-03-30 | — | — | EP | claimed |
| EP-0071370-A2 | Cephalosporin derivatives, process for their preparation and pharmaceutical compositions containing them | ICI PHARMA (FR) | 1983-02-09 | — | — | EP | claimed |
| EP-0031708-A2 | Cephalosporin derivatives, processes for their manufacture, pharmaceutical compositions containing them and intermediates therefor | ICI PHARMA (FR) | 1981-07-08 | — | — | EP | claimed |
| US-11026910-B2 | α- and γ-truxillic acid derivatives and pharmaceutical compositions thereof | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2021-06-08 | — | — | US | disclosed |
| EP-2874987-B1 | alpha-AND gamma-TRUXILLIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS THEREOF | UNIV NEW YORK STATE RES FOUND (US) | 2020-03-25 | — | — | EP | disclosed |
| US-20190201365-A1 | ALPHA- AND GAMMA-TRUXILLIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS THEREOF | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2019-07-04 | — | — | US | disclosed |
| CN-109415295-A | α-truxillic acid derivative and its pharmaceutical composition | 纽约州立大学研究基金会 | 2019-03-01 | — | — | CN | disclosed |
| US-20170216241-A1 | ALPHA- AND GAMMA-TRUXILLIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS THEREOF | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2017-08-03 | — | — | US | disclosed |
| US-9604904-B2 | Alpha- and gamma-truxillic acid derivatives and pharmaceutical compositions thereof | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2017-03-28 | — | — | US | disclosed |
| US-20150183715-A1 | ALPHA- AND GAMMA-TRUXILLIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS THEREOF | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2015-07-02 | — | — | US | disclosed |
| EP-2874987-A1 | alpha-AND gamma-TRUXILLIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS THEREOF | The Research Foundation Of State University Of New York (US) | 2015-05-27 | — | — | EP | disclosed |
| US-4486426-A | BACTERICIDAL ANTIBIOTICS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-12-04 | — | — | US | disclosed |
| US-4463173-A | ANTIBIOTIC, BACTERICIDE | ICI PHARMA (FR) | 1984-07-31 | — | — | US | disclosed |
| EP-0031708-B1 | CEPHALOSPORIN DERIVATIVES, PROCESSES FOR THEIR MANUFACTURE, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND INTERMEDIATES THEREFOR | ICI PHARMA (FR) | 1984-06-13 | — | — | EP | disclosed |
| EP-0075434-A2 | Cephalosporins, their preparation and their pharmaceutical compositions | ICI PHARMA (FR) | 1983-03-30 | — | — | EP | disclosed |
| EP-0071370-A2 | Cephalosporin derivatives, process for their preparation and pharmaceutical compositions containing them | ICI PHARMA (FR) | 1983-02-09 | — | — | EP | disclosed |
| EP-0031708-A2 | Cephalosporin derivatives, processes for their manufacture, pharmaceutical compositions containing them and intermediates therefor | ICI PHARMA (FR) | 1981-07-08 | — | — | EP | disclosed |
| US-4035426-A | Diarylcyclobutanes | MEAD JOHNSON & COMPANY (US) | 1977-07-12 | — | — | US | disclosed |
| US-3939196-A | Diarylcyclobutanes | MEAD JOHNSON & COMPANY (US) | 1976-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190201365-A1 | ALPHA- AND GAMMA-TRUXILLIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS THEREOF | FABP1, FABP2, FABP7 | OPRM1 791/4885MEN1 4872/4885CYP2C9 2127/4885 |
| US-11026910-B2 | α- and γ-truxillic acid derivatives and pharmaceutical compositions thereof | FABP1, FABP2, FABP4 | OPRM1 851/4885MEN1 4873/4885CYP2C9 1973/4885 |
| US-20150183715-A1 | ALPHA- AND GAMMA-TRUXILLIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS THEREOF | FABP1, FABP2, FABP7 | OPRM1 791/4885MEN1 4872/4885CYP2C9 2127/4885 |
| US-20170216241-A1 | ALPHA- AND GAMMA-TRUXILLIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS THEREOF | FABP1, FABP2, FABP7 | OPRM1 791/4885MEN1 4872/4885CYP2C9 2127/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.