Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDFT1 | P37268 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 2/20 | 0.31 |
| ▸ | MMP13 | P45452 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8772751 | 1.00 | FDFT1 (0.37) | FDFT1CHRM2CHRM4CHRM5CHRM1 | |
| Hydrochloric Acid SCHEMBL8772602 | 0.86 | FDFT1 (0.42) | FDFT1MAPTHTTALDH1A1LMNA | |
| SCHEMBL8772588 | 0.83 | PTGDR (0.39) | FDFT1MAPTTDP1HTTMMP13 | |
| SCHEMBL9150829 | 0.82 | FDFT1 (0.41) | FDFT1CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL8772635 | 0.81 | FDFT1 (0.46) | FDFT1MMP13ALDH1A1LMNAKMT2A | |
| SCHEMBL8772637 | 0.80 | FDFT1 (0.38) | FDFT1MAPTTDP1HTTALDH1A1 | |
| SCHEMBL8772603 | 0.80 | FDFT1 (0.45) | FDFT1MMP13ALDH1A1LMNAKMT2A | |
| Hydrochloric Acid SCHEMBL8772650 | 0.80 | FDFT1 (0.37) | FDFT1MAPTTDP1HTTALDH1A1 | |
| SCHEMBL8772687 | 0.80 | FDFT1 (0.37) | FDFT1MAPTTDP1HTTALDH1A1 | |
| SCHEMBL8421904 | 0.79 | MAPT (0.42) | FDFT1MAPTTDP1POLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0654032-B1 | QUINUCLIDINE DERIVATIVES AS SQUALENE SYNTHASE INHIBITORS | ZENECA LTD (GB) | 1997-10-15 | — | — | EP | disclosed |
| WO-1994003451-A1 | QUINUCLIDINE DERIVATIVES AS SQUALENE SYNTHASE INHIBITORS | ZENECA LIMITED (GB) | 1994-02-17 | — | — | WO | disclosed |