Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDFT1 | P37268 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 4/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8421585 | 0.85 | FDFT1 (0.41) | FDFT1KDM4EGABRA1GABRB2CNR2 | |
| SCHEMBL8423284 | 0.85 | FDFT1 (0.41) | FDFT1KDM4EGABRA1GABRB2ALDH1A1 | |
| SCHEMBL8772748 | 0.82 | FDFT1 (0.37) | FDFT1ALDH1A1CHRM2CHRM4CHRM5 | |
| SCHEMBL8772751 | 0.82 | FDFT1 (0.37) | FDFT1ALDH1A1CHRM2CHRM4CHRM5 | |
| Hydrochloric Acid SCHEMBL8772602 | 0.81 | FDFT1 (0.42) | FDFT1ALDH1A1TSHRMAPT | |
| SCHEMBL8421904 | 0.80 | MAPT (0.42) | FDFT1KDM4EALDH1A1MAPT | |
| SCHEMBL8565534 | 0.79 | FDFT1 (0.66) | FDFT1KDM4EGABRA1GABRB2ALDH1A1 | |
| SCHEMBL8421714 | 0.79 | MAPT (0.42) | FDFT1KDM4EALDH1A1MAPT | |
| SCHEMBL8420308 | 0.78 | FDFT1 (0.65) | FDFT1KDM4EGABRA1GABRB2ALDH1A1 | |
| SCHEMBL9150823 | 0.78 | FDFT1 (0.35) | FDFT1KDM4EALDH1A1CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0654032-A1 | QUINUCLIDINE DERIVATIVES AS SQUALENE SYNTHASE INHIBITORS. | ZENECA LTD (GB) | 1995-05-24 | — | — | EP | disclosed |