Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDFT1 | P37268 | 2/20 | 0.73 |
| ▸ | MMP13 | P45452 | 13/20 | 0.60 |
| ▸ | MMP2 | P08253 | 5/20 | 0.44 |
| ▸ | MMP12 | P39900 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8968803 | 0.91 | FDFT1 (0.65) | FDFT1MMP13MMP2MMP12 | |
| SCHEMBL8968489 | 0.89 | FDFT1 (0.61) | FDFT1MMP13MMP2MMP12 | |
| SCHEMBL8968319 | 0.89 | FDFT1 (0.68) | FDFT1MMP13MMP2MMP12 | |
| SCHEMBL8968321 | 0.89 | FDFT1 (0.78) | FDFT1MMP13MMP2MMP12 | |
| SCHEMBL8772583 | 0.88 | MMP13 (0.63) | FDFT1MMP13MMP2MMP12 | |
| SCHEMBL8772671 | 0.88 | FDFT1 (0.65) | FDFT1MMP13MMP2MMP12 | |
| SCHEMBL8968958 | 0.86 | MMP13 (0.59) | FDFT1MMP13MMP2 | |
| SCHEMBL9432075 | 0.86 | FDFT1 (0.84) | FDFT1MMP13MMP2 | |
| SCHEMBL27437221 | 0.85 | FDFT1 (0.77) | FDFT1MMP13MMP2 | |
| SCHEMBL9432346 | 0.84 | FDFT1 (0.73) | FDFT1MMP13MMP2MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0654032-B1 | QUINUCLIDINE DERIVATIVES AS SQUALENE SYNTHASE INHIBITORS | ZENECA LTD (GB) | 1997-10-15 | — | — | EP | claimed |
| EP-0654032-A1 | QUINUCLIDINE DERIVATIVES AS SQUALENE SYNTHASE INHIBITORS. | ZENECA LTD (GB) | 1995-05-24 | — | — | EP | claimed |
| WO-1994003451-A1 | QUINUCLIDINE DERIVATIVES AS SQUALENE SYNTHASE INHIBITORS | ZENECA LIMITED (GB) | 1994-02-17 | — | — | WO | claimed |
| EP-0654032-B1 | QUINUCLIDINE DERIVATIVES AS SQUALENE SYNTHASE INHIBITORS | ZENECA LTD (GB) | 1997-10-15 | — | — | EP | disclosed |
| EP-0654032-A1 | QUINUCLIDINE DERIVATIVES AS SQUALENE SYNTHASE INHIBITORS. | ZENECA LTD (GB) | 1995-05-24 | — | — | EP | disclosed |
| WO-1994003451-A1 | QUINUCLIDINE DERIVATIVES AS SQUALENE SYNTHASE INHIBITORS | ZENECA LIMITED (GB) | 1994-02-17 | — | — | WO | disclosed |