Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 13/20 | 0.63 |
| ▸ | FDFT1 | P37268 | 2/20 | 0.59 |
| ▸ | MMP2 | P08253 | 7/20 | 0.46 |
| ▸ | MMP12 | P39900 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8968958 | 0.91 | MMP13 (0.59) | MMP13FDFT1MMP2 | |
| SCHEMBL8772804 | 0.88 | FDFT1 (0.73) | MMP13FDFT1MMP2MMP12 | |
| SCHEMBL8772636 | 0.81 | MMP13 (0.90) | MMP13FDFT1MMP2MMP12 | |
| SCHEMBL8772840 | 0.80 | MMP13 (0.70) | MMP13FDFT1MMP2 | |
| SCHEMBL8968803 | 0.78 | FDFT1 (0.65) | MMP13FDFT1MMP2MMP12 | |
| SCHEMBL8968321 | 0.77 | FDFT1 (0.78) | MMP13FDFT1MMP2MMP12 | |
| SCHEMBL8968489 | 0.77 | FDFT1 (0.61) | MMP13FDFT1MMP2MMP12 | |
| Hydrochloric Acid SCHEMBL8772550 | 0.76 | MMP13 (0.45) | MMP13FDFT1 | |
| SCHEMBL8969498 | 0.76 | FDFT1 (0.55) | MMP13FDFT1MMP2 | |
| SCHEMBL6382345 | 0.75 | FDFT1 (0.54) | MMP13FDFT1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0654032-B1 | QUINUCLIDINE DERIVATIVES AS SQUALENE SYNTHASE INHIBITORS | ZENECA LTD (GB) | 1997-10-15 | — | — | EP | disclosed |
| EP-0654032-A1 | QUINUCLIDINE DERIVATIVES AS SQUALENE SYNTHASE INHIBITORS. | ZENECA LTD (GB) | 1995-05-24 | — | — | EP | disclosed |
| WO-1994003451-A1 | QUINUCLIDINE DERIVATIVES AS SQUALENE SYNTHASE INHIBITORS | ZENECA LIMITED (GB) | 1994-02-17 | — | — | WO | disclosed |