SCHEMBL8772862

SCHEMBL8772862

NCCOCCS(=O)(=O)O

nearest known ligand 0.55

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.55
SLC6A6 P31641 1/20 0.55
CYP2C19 P33261 1/20 0.55
BLM P54132 1/20 0.55
APP P05067 1/20 0.50
PTGS1 P23219 1/20 0.42
PDE4A P27815 1/20 0.42
CXCL10 P02778 1/20 0.30
CXCL8 P10145 1/20 0.30
CCL2 P13500 1/20 0.30
CCL5 P13501 1/20 0.30
CXCL12 P48061 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16329223 0.98 LMNA (0.52) LMNASLC6A6CYP2C19BLMAPP
SCHEMBL418534 0.87 PTGS1 (0.53) LMNASLC6A6CYP2C19BLMAPP
SCHEMBL9988925 0.84 APP (0.56) LMNASLC6A6CYP2C19BLMAPP
Sulfuric Acid SCHEMBL8719034 0.84 BLM (0.43) LMNASLC6A6CYP2C19BLMAPP
SCHEMBL7869938 0.84 PTGS1 (0.50) LMNASLC6A6CYP2C19BLMAPP
SCHEMBL28038731 0.84 PTGS1 (0.50) LMNASLC6A6CYP2C19BLMAPP
SCHEMBL3488844 0.80 PTGS1 (0.42) LMNASLC6A6CYP2C19BLMAPP
SCHEMBL8495567 0.78 LMNA (0.36) LMNASLC6A6CYP2C19BLMAPP
SCHEMBL263732 0.77 APP (0.46) LMNASLC6A6CYP2C19BLMAPP
SCHEMBL375597 0.77 TSHR (0.53) LMNASLC6A6CYP2C19BLMAPP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230131121-A1 BRANCHED DISCRETE PEG CONSTRUCTS AUDAX PRIVATE DEBT LLC, AS AGENT 2023-04-27 US disclosed
EP-0628860-B1 New type of modified gelatin and its use in a DTR material AGFA GEVAERT NV (BE) 1997-10-15 EP disclosed
US-5536817-A DIFFUSION TRANSFER REVERSAL AGFA-GEVAERT, N.V. (BE) 1996-07-16 US disclosed
US-5474885-A Hydrophilic photographic diffusion transfer reversal material containing gelatin modified by sulfate, sulfonate, phosphate, or phosphonate groups, for lithographic printing plates AGFA-GEVAERT, N.V. (BE) 1995-12-12 US disclosed
EP-0628860-A1 New type of modified gelatin and its use in a DTR material AGFA-GEVAERT N.V. (BE) 1994-12-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230131121-A1 BRANCHED DISCRETE PEG CONSTRUCTS BTD, IDUA, DNPEP LMNA 1957/4885SLC6A6 4381/4885CYP2C19 1671/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.