Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 11/20 | 0.67 |
| ▸ | FCER2 | P06734 | 4/20 | 0.67 |
| ▸ | MMP2 | P08253 | 13/20 | 0.56 |
| ▸ | MMP7 | P09237 | 9/20 | 0.56 |
| ▸ | MMP9 | P14780 | 7/20 | 0.56 |
| ▸ | MMP12 | P39900 | 1/20 | 0.56 |
| ▸ | MMP13 | P45452 | 1/20 | 0.56 |
| ▸ | MMP3 | P08254 | 10/20 | 0.54 |
| ▸ | MMP8 | P22894 | 6/20 | 0.54 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27496760 | 1.00 | MMP1 (0.67) | MMP1FCER2MMP2MMP7MMP9 | |
| SCHEMBL27559917 | 0.87 | MMP1 (0.74) | MMP1FCER2MMP2MMP7MMP9 | |
| SCHEMBL8892940 | 0.87 | MMP1 (0.74) | MMP1FCER2MMP2MMP7MMP9 | |
| SCHEMBL8772905 | 0.81 | MMP1 (0.75) | MMP1FCER2MMP2MMP7MMP9 | |
| SCHEMBL7368611 | 0.78 | MMP1 (0.74) | MMP1FCER2MMP2MMP7MMP9 | |
| SCHEMBL7368615 | 0.78 | MMP1 (0.74) | MMP1FCER2MMP2MMP7MMP9 | |
| SCHEMBL7368616 | 0.78 | MMP1 (0.74) | MMP1FCER2MMP2MMP7MMP9 | |
| SCHEMBL7370918 | 0.78 | MMP1 (0.93) | MMP1FCER2MMP2MMP7MMP9 | |
| SCHEMBL7370922 | 0.78 | MMP1 (0.93) | MMP1FCER2MMP2MMP7MMP9 | |
| SCHEMBL7370927 | 0.78 | MMP1 (0.93) | MMP1FCER2MMP2MMP7MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0800510-A1 | HYDROXAMIC ACID-CONTAINING INHIBITORS OF MATRIX METALLOPROTEASES | THE PROCTER & GAMBLE COMPANY (US) | 1997-10-15 | — | — | EP | claimed |
| US-5639746-A | INHIBITORS OF METALLOPROTEASE | THE PROCTER & GAMBLE COMPANY (US) | 1997-06-17 | — | — | US | claimed |
| WO-1996020918-A1 | HYDROXAMIC ACID-CONTAINING INHIBITORS OF MATRIX METALLOPROTEASES | THE PROCTER & GAMBLE COMPANY (US) | 1996-07-11 | — | — | WO | claimed |
| US-5639746-A | INHIBITORS OF METALLOPROTEASE | THE PROCTER & GAMBLE COMPANY (US) | 1997-06-17 | — | — | US | disclosed |