Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 6/20 | 0.74 |
| ▸ | FCER2 | P06734 | 4/20 | 0.74 |
| ▸ | MMP9 | P14780 | 11/20 | 0.61 |
| ▸ | MMP2 | P08253 | 9/20 | 0.61 |
| ▸ | MMP7 | P09237 | 3/20 | 0.61 |
| ▸ | MMP12 | P39900 | 2/20 | 0.61 |
| ▸ | MMP13 | P45452 | 2/20 | 0.61 |
| ▸ | MMP8 | P22894 | 10/20 | 0.59 |
| ▸ | MMP3 | P08254 | 2/20 | 0.59 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.52 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.52 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.52 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27559917 | 1.00 | MMP1 (0.74) | MMP1FCER2MMP9MMP2MMP7 | |
| SCHEMBL27496760 | 0.87 | MMP1 (0.67) | MMP1FCER2MMP9MMP2MMP7 | |
| SCHEMBL8772909 | 0.87 | MMP1 (0.67) | MMP1FCER2MMP9MMP2MMP7 | |
| SCHEMBL7370922 | 0.83 | MMP1 (0.93) | MMP1FCER2MMP9MMP2MMP7 | |
| SCHEMBL7370918 | 0.83 | MMP1 (0.93) | MMP1FCER2MMP9MMP2MMP7 | |
| SCHEMBL7370927 | 0.83 | MMP1 (0.93) | MMP1FCER2MMP9MMP2MMP7 | |
| SCHEMBL7383258 | 0.80 | MMP1 (0.87) | MMP1FCER2MMP9MMP2MMP7 | |
| SCHEMBL27496411 | 0.78 | FCER2 (0.67) | MMP1FCER2MMP9MMP2MMP7 | |
| SCHEMBL8772902 | 0.78 | FCER2 (0.67) | MMP1FCER2MMP9MMP2MMP7 | |
| SCHEMBL8895943 | 0.76 | MMP1 (0.72) | MMP1FCER2MMP9MMP2MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5639746-A | INHIBITORS OF METALLOPROTEASE | THE PROCTER & GAMBLE COMPANY (US) | 1997-06-17 | — | — | US | claimed |
| US-5639746-A | INHIBITORS OF METALLOPROTEASE | THE PROCTER & GAMBLE COMPANY (US) | 1997-06-17 | — | — | US | disclosed |