Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 known ✓ | P35372 | 14/20 | 0.77 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.77 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.77 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.70 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11569120 | 0.98 | OPRM1 (0.80) | OPRM1OPRD1OPRK1CACNA1COPRL1 | |
| Oxalic Acid SCHEMBL6045761 | 0.91 | OPRM1 (0.67) | OPRM1OPRD1OPRK1CACNA1C | |
| Carfentanil SCHEMBL9737212 | 0.89 | OPRM1 (0.96) | OPRM1OPRD1OPRK1CACNA1COPRL1 | |
| Oxalic Acid SCHEMBL19178214 | 0.89 | OPRM1 (0.61) | OPRM1OPRD1OPRK1CACNA1C | |
| SCHEMBL6045500 | 0.89 | OPRM1 (0.69) | OPRM1OPRD1OPRK1CACNA1C | |
| SCHEMBL19193773 | 0.89 | OPRM1 (0.67) | OPRM1OPRD1OPRK1CACNA1COPRL1 | |
| SCHEMBL10843110 | 0.88 | OPRM1 (0.66) | OPRM1OPRD1OPRK1CACNA1C | |
| Oxalic Acid SCHEMBL6045472 | 0.87 | OPRM1 (0.59) | OPRM1OPRD1OPRK1CACNA1C | |
| Carfentanil SCHEMBL116222 | 0.87 | OPRM1 (1.00) | OPRM1OPRD1OPRK1CACNA1COPRL1 | |
| [11C]-Carfentanil SCHEMBL29374424 | 0.87 | OPRM1 (1.00) | OPRM1OPRD1OPRK1CACNA1COPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3199523-A1 | THE NEW PROCESS FOR PRODUCING N-PHENYL-N-(4-PIPERIDINYL) AMIDE DERIVATIVES SUCH AS REMIFENTANIL AND CARFENTANIL | Bioka s. r.o. (SK) | 2017-08-02 | — | — | EP | disclosed |
| EP-0638554-B1 | Process for producing a N-phenyl-N-(4-piperidinyl) amide derivative | GLAXO GROUP LTD (GB) | 1997-10-22 | — | — | EP | disclosed |
| US-5599938-A | Process for preparing a piperidine derivative | GLAXO GROUP LIMITED (GB) | 1997-02-04 | — | — | US | disclosed |
| EP-0638554-A1 | Process for producing a N-phenyl-N-(4-piperidinyl) amide derivative | GLAXO GROUP LIMITED (GB) | 1995-02-15 | — | — | EP | disclosed |