Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.53 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | ESPL1 | Q14674 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9427812 | 0.90 | ALDH3A1 (0.49) | ALDH3A1HCAR3ALDH1A1MAPK1MAPT | |
| SCHEMBL3110151 | 0.81 | ALDH3A1 (0.54) | ALDH3A1HCAR3ALDH1A1MAPK1MAPT | |
| SCHEMBL10687975 | 0.78 | ATM (0.53) | ALDH3A1HCAR3ALDH1A1MAPK1MAPT | |
| SCHEMBL14180498 | 0.76 | TDP1 (0.55) | ALDH3A1HCAR3ALDH1A1MAPK1MAPT | |
| SCHEMBL6152063 | 0.76 | ALDH1A1 (0.53) | ALDH3A1HCAR3ALDH1A1MAPK1MAPT | |
| SCHEMBL7545601 | 0.76 | ALDH3A1 (0.46) | ALDH3A1HCAR3ALDH1A1MAPK1MAPT | |
| SCHEMBL24900630 | 0.75 | ALDH3A1 (0.40) | ALDH3A1HCAR3ALDH1A1MAPK1MAPT | |
| SCHEMBL30221477 | 0.75 | ALDH3A1 (0.40) | ALDH3A1HCAR3ALDH1A1MAPK1MAPT | |
| SCHEMBL45486 | 0.74 | TDP1 (0.60) | ALDH1A1MAPK1MAPTMEN1RAB9A | |
| SCHEMBL9848594 | 0.74 | MEN1 (0.56) | ALDH3A1ALDH1A1MAPTMEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0439585-B1 | IMMOBILISATION OF LIGANDS BY RADIO-DERIVATIZED POLYMERS | MAG GEORG MAYRHOFER & CO OHG (AT) | 1997-10-29 | — | — | EP | disclosed |
| US-5196478-A | Polystyrene, assays | EPIPHARM ALLERGIE-SERVICE GESELLSCHAFT M.B.H. (AT) | 1993-03-23 | — | — | US | disclosed |
| EP-0439585-A1 | IMMOBILISATION OF LIGANDS BY RADIO-DERIVATIZED POLYMERS. | EPIPHARM ALLERGIE SERVICE (AT) | 1991-08-07 | — | — | EP | disclosed |
| WO-1991002768-A1 | IMMOBILISATION OF LIGANDS BY RADIO-DERIVATIZED POLYMERS | EPIPHARM ALLERGIE-SERVICE GESELLSCHAFT M.B.H. (AT) | 1991-03-07 | — | — | WO | disclosed |