Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 3/20 | 0.47 |
| ▸ | ESR1 | P03372 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | HPGDS | O60760 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MERTK | Q12866 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24690169 | 0.84 | GRM5 (0.51) | GRM5MAPTHPGDKDM4EPOLB | |
| SCHEMBL30020111 | 0.84 | GRM5 (0.51) | GRM5MAPTHPGDKDM4EPOLB | |
| SCHEMBL23943606 | 0.83 | GRM5 (0.43) | GRM5MAPTKDM4EMAPK1L3MBTL1 | |
| SCHEMBL11296944 | 0.82 | GRM5 (0.51) | GRM5ALDH1A1KDM4EHPGDSLMNA | |
| SCHEMBL18049170 | 0.81 | GRM5 (0.51) | GRM5ALDH1A1MAPTHPGDKDM4E | |
| SCHEMBL20239278 | 0.80 | PGR (0.47) | GRM5ALDH1A1HPGDMAPK1MEN1 | |
| SCHEMBL16739535 | 0.78 | MAPT (0.63) | ESR1ALDH1A1MAPTHPGDKDM4E | |
| SCHEMBL23504272 | 0.77 | GRM5 (0.65) | GRM5LMNASMN1; SMN2 | |
| SCHEMBL18249762 | 0.77 | GRM5 (0.44) | GRM5ESR1ALDH1A1KDM4EMEN1 | |
| SCHEMBL20239277 | 0.76 | GRM5 (0.45) | GRM5ESR1ALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691277-A | REACTING A 2,6-DIHALOGENOPYRIDINE WITH A META SUBSTITUTED PHENOL | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1997-11-25 | — | — | US | disclosed |
| EP-0692474-B1 | 2- (unsubstituted or substituted) (benzyloxy or phenoxy)-4-substituted-6-(meta-substituted phenoxy) pyridine, process for producing the same, and herbicidal composition | KUREHA CHEMICAL IND CO LTD (JP) | 1997-10-29 | — | — | EP | disclosed |
| EP-0692474-A1 | 2- (unsubstituted or substituted) (benzyloxy or phenoxy)-4-substituted-6-(meta-substituted phenoxy) pyridine, process for producing the same, and herbicidal composition | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1996-01-17 | — | — | EP | disclosed |