Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8031606 | 0.89 | MAPT (0.43) | MAPTSMN1; SMN2KDM4ERAB9ANPC1 | |
| SCHEMBL29350030 | 0.89 | SMN1; SMN2 (0.47) | MAPTSMN1; SMN2KDM4ERAB9ANPC1 | |
| SCHEMBL7598576 | 0.89 | SMN1; SMN2 (0.47) | MAPTSMN1; SMN2KDM4ERAB9ANPC1 | |
| SCHEMBL8773258 | 0.81 | MAPT (0.43) | MAPTCA2 | |
| SCHEMBL8031502 | 0.71 | CA2 (0.50) | MAPTSMN1; SMN2KDM4ERAB9ANPC1 | |
| SCHEMBL8381667 | 0.69 | MAOB (0.46) | MAPTRAB9ANPC1KMT2AMEN1 | |
| SCHEMBL11058650 | 0.68 | CA2 (0.68) | KDM4EPKMKMT2ATDP1CA2 | |
| Phenyl Dihydrogen Phosphate SCHEMBL29249086 | 0.67 | SRC (0.54) | MAPTSMN1; SMN2RAB9ANPC1PKM | |
| Phenyl Dihydrogen Phosphate SCHEMBL29249081 | 0.67 | SRC (0.54) | MAPTSMN1; SMN2RAB9ANPC1PKM | |
| SCHEMBL8165788 | 0.66 | INPPL1 (0.41) | MAPTSMN1; SMN2RAB9ANPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0424465-B1 | PREPARATION AND USE OF FLUORESCENT BENZOTHIAZOLE DERIVATIVES | JBL SCIENT INC (US) | 1997-10-29 | — | — | EP | disclosed |